基于关联规则分析明清古籍中疫病文献的药-症关系  

Research on the Relationship between Drugs and Symptoms about Epidemic Febrile Disease Treated by Doctors of Ming and Qing Dynasties Based on Bidirectional

作　　者：李文林[1] 屠强[2] 彭丽坤[3] 程茜[1] 陈仁寿[3] 

机构地区：[1]南京中医药大学图书馆中医药信息检索中心,江苏南京210046 [2]南京理工大学计算机科学与技术学院,江苏南京210094 [3]南京中医药大学文献研究所,江苏南京210046

出　　处：《时珍国医国药》2010年第4期957-959,共3页Lishizhen Medicine and Materia Medica Research

基　　金：江苏省自然科学基金(No.BK2008460);江苏省中医药局科研项目(No.HL07071)

摘　　要：目的分析明清两代15本医籍、医案、医话中660例疫病诊疗的方药特色及药症关系。方法基于关联规则挖掘。结果在单味药及药对与症状之间均发现了一些有意义的关联关系。显示疫病总属热邪为患,易伤及营血、易耗伤气阴。治疗以清热为大法,主用清热药。急证清心醒神,善用开窍药。后期补虚扶正,重用补益药。清热药物中,清气分热药最多,清热凉血药次之,解表药常常随症加减,说明"入营犹可透热转气"的理论在疫病的治疗中具有一定的应用价值。结论数据挖掘的结果与中医疫病的治法及用药基本相符,能初步揭示明清医家对疫病诊疗的学术思想及治疫经验。Objective To study the relationship between drugs and symptoms about epidemic febrile disease （EFD） treated by doctors of Ming and Qing dynasties. Methods Data mining of bidirectional association rules. Results A total of 15 medical books which contain 660 cases of prescription of Ming and Qing dynasties were collectd, and some interesting rules about traditional Chinese medicine and the disease symptoms were selected in the high frequency distribution. The results suggested that heat was the main pathogen of epidemic febrile disease , and it easily tended to develop to ＂Yin＂ impaired,＂ Qi＂ and blood consumed . According to the diagnosis, heat clearing, nourishing ＂Yin＂ and reinforcing ＂Qi＂ were the main treatment methods. Additionally, medicinal, fragrant in flavor, with a resuscitating effect often used for emergent treatment in time of loss of consciousness . Conclusion The method can find out some interesting rules about the comprehensive principle in EFD planning treatment.

关 键 词：疫病 关联规则 药-症关系 明清 

分 类 号：R249[医药卫生—中医临床基础]