两起水痘暴发疫情的疫苗保护效果调查  

Survey of two outbreaks of varicella and analysis of protective effect of vaccine

作　　者：于文博[1] 安向东[1] 李艳春[2] 连志勇[1] 

机构地区：[1]沈阳市疾病预防控制中心,辽宁沈阳110031 [2]沈阳市铁西区疾病预防控制中心,辽宁沈阳110031

出　　处：《中国热带医学》2010年第6期684-684,686,共2页China Tropical Medicine

摘　　要：目的通过对两所水痘疫情暴发学校学生进行的病例对照研究,调查水痘疫苗接种后的保护效果。方法采用1:1配对的病例对照研究,通过问卷调查获得免疫接种等相关信息,并进行统计学分析。结果平均接种水痘疫苗3年后,疫苗的保护率为67%,7年后疫苗的保护率下降为43%。结论提示水痘疫苗的保护率随着时间的推移而逐渐降低;接种过水痘疫苗学生发生水痘时症状较未接种疫苗者发病症状要轻。Aim To survey two outbreaks of vericella in two schools of Shenyang and evaluate the protective effect of vaccine. Methods Case-control study was conducted and questionaire survey was carried out. Results The protection rate of the vaccine in the three years following varicella vaccination was 67% ,a drop of 43% 7 years after vaccination. Conclusion The effectiveness of the varicella vaccination gradually drops over time.

关 键 词：水痘 暴发 保护率 病例对照研究 

分 类 号：R511.5[医药卫生—内科学]