不同年龄组妊娠高血压疾病孕妇空腹血糖正常者糖耐量试验对比研究  

The eomparation of oral glueose tolerance test in pregnancy-induced hypertension pa- tients with normal fasting blood-glucose of different age

作　　者：向祚再 段红艳[1] 梁汉华[1] 王敏[1] 载晓燕 刘荣辉[3] 唐美良 樊玲清 潘秋玲[1] 黎小云[1] 

机构地区：[1]惠州市大亚湾区人民医院,516081 [2]惠州市惠城区红十字会医院妇产科,516083 [3]惠州市惠阳区人民医院妇产科,516003 [4]湖南省溆浦县人民医院妇产科,419300

出　　处：《国际医药卫生导报》2010年第7期776-779,共4页International Medicine and Health Guidance News

基　　金：2009年惠州市科技计划项目（2009Y106）

摘　　要：目的探讨不同年龄组妊娠高血压疾病孕妇空腹血糖（FPG）正常者葡萄糖耐受能力的差别。方法将妊娠高血压孕妇FPG正常者纳入观察组，正常妊娠者纳入对照组。观察组从20周岁到45周岁按每5周岁为一年龄段各设5个小组，即：≥20周岁为A组，≥25周岁为B组，≥30周岁为C组，≥35周岁为D组，≥40周岁、〈45周岁为E组。每小组各按时间顺序入选病例31、32、33、34、30例。入选对象在孕37周加1至38周时进行空腹葡萄糖耐量试验（OGTT），然后将观察组各小组2小时血糖值（2hPG）进行比较，并与对照组35例对比分析。结果观察组各小组2hPG水平均高于对照组，而且，随着年龄增加愈加显著，其中c组与B组、D组与c组、E组与D组比较均有非常显著意义（P〈0．01）；观察组各小组2hPG升高率均高于对照组，观察组随着年龄增长2hPG升高率逐渐增加，其中E组与D组、D组与C组比较均有统计学意义（P〈0．05）。结论妊娠高血压疾病孕妇FPG正常者葡萄糖耐受能力显著下降。年龄可作为妊娠高血压疾病孕妇糖代谢障碍的预测因素。Objective To discuss the difference of oral glucose tolerance in pregnancy-induced hypertension patients with normal fasting plasma glucose （ FPG ） of different age. Methods Set pregnancy-induced hypertension patients with normal fasting blood-glucose as observation group and normal pregnant women as control group. Observation group were divided into 5 groups according to their age. Group A： =20 years old （ 31 patients ）. Group B： =25 years old （ 32 patients ）. Group C： =30 years old （ 33 patients ）. Group D： =35 years old （ 34 patients ）. Group E： =40 years old, and 〈 45 years old （ 30 patients ）. Results The 2hPG in each observation group were all higher than control, and with the increase of age, the difference were more evident. The difference between group C and group B, group D and group C, group E and group D were statistical significance （ P〈 0.01 ）. The pressure rise rate of 2hPG in each observation group were all higher than control, and with the increase of age, the difference were more evident. The difference between group D and group C, group E and group D were statistical significance（ p〈0.05 ）.Conclusins The oral glucose tolerance of pregnancy-induced hypertension patients with normal fasting blood-glucose decreases sharply. Age can be considered as a predictor of dysbolism in pregnancyinduced hypertension patients.

关 键 词：不同年龄 妊娠高血压疾病 空腹血糖 糖耐量试验 

分 类 号：R714[医药卫生—妇产科学]