白头翁复方对腹泻小鼠肠道粘膜乳糖酶活性的影响  

The influence of decoction of compound Radix pulsatillae on the lactase activity in diarrheal mice intestinal mucosa

作　　者：张晓利[1] 王迎春[1] 徐倩倩[1] 王丽叶[1] 霍晓青[1] 曹玲芝[1] 张永辉 董世山[1] 

机构地区：[1]河北农业大学动物科技学院,河北保定071001 [2]衡水市动物疫病预防控制中心,河北衡水053000

出　　处：《河北农业大学学报》2010年第2期99-102,共4页Journal of Hebei Agricultural University

基　　金：河北省自然科学基金项目(C2008000334);国家十一五重大专项子专题(2006BAD04A1024);河北省科技支撑计划项目(07220401D-01)

摘　　要：为了探讨白头翁复方对腹泻小鼠肠道粘膜乳糖酶活性的影响,取体重相近BALB/c小鼠180只,随机分预防组、治疗组、自愈组和对照组,每组45只,本试验采用Dahlqvist的方法测定各组小鼠前、中、后段肠道粘膜乳糖酶的活性。结果表明:预防组和治疗组乳糖酶的活性显著高于自愈组(P<0.01),预防组和治疗组的差异不显著(P>0.05)。说明白头翁复方能够显著增强腹泻小鼠肠道粘膜上乳糖酶的活性,表明白头翁复方治疗腹泻的作用机理可能与调节乳糖酶的活性有关。To investigate the regulatory effects of decoction of compound Radix pulsatillae on the activities of lactase in the intestinal mucosal cells of diarrheal mice,180 BALB/c mice were randomly divided into prevention group,treatment group,autotherapy group and control group with 45 mice in each group.The activities of lactase in the intestinal mucosal cells in diarrheal mice were determined by the modified method of Dahlqvis.The results showed as follows： the lactase activities of prevention group and treatment group were significantly higher than that of autotherapy group（P0.01）.Prevention group and treatment group had no diversities.Decoction of compound Radix pulsatillae can treat diarrheal,and maybe this is caused by the activities of lactase.

关 键 词：白头翁 小鼠 腹泻 肠道粘膜 乳糖酶 

分 类 号：S852.3[农业科学—基础兽医学]