病毒性心肌炎患者外周血红细胞免疫功能的变化和血清cTnI水平的相关性分析  

Study on the Relationship Between Peripheral Blood Red Blood Cells Immunofunction Status and Serum cTnI Levels in Patients with Viral Myocarditis

作　　者：章惠刚[1] 付美丽[1] 赵沛光[1] 李建祖[1] 

机构地区：[1]江苏省东海县人民医院,222300

出　　处：《放射免疫学杂志》2010年第2期203-205,共3页Journal of Radioimmanology

摘　　要：目的:探讨了病毒性心肌炎患者外周血红细胞免疫功能的变化和血清肌钙蛋白(cTnI)水平的相关性。方法:应用电化学发光法和免疫法对40例病毒性心肌炎患者进行了血清cTnI水平和红细胞免疫功能测定,并与35名正常健康人作比较。结果:病毒性心肌炎患者RBC-C3bRR水平明显降低(P<0.01),而血清cTnI水平则显著升高(P<0.01)。RBC-C3bRR水平与血清cTnI水平呈显著负相关(r=-0.3688,P<0.05)。而RBC-ICRR水平则显著高于正常人水平(P<0.01),与血清cTnI水平呈显著正相关(r=0.3784,P<0.05)。结论:病毒性心肌炎患者存在免疫调节的紊乱,免疫功能低下与血清cTnI水平有一定的相关性。Objective To investigate the relationship between changes of peripheral blood red blood cells immunofuntion status and serum cTnI level in patients with viral myocarditis. Methods RBC immunofunction status was studied with immunologic methods and serum cTnI levels were measured with electrochemiluminescence immunoassay in 40 patients with viral myocarditis and 35 controls. Results Levels of RBC-C3bRR were significantly lower and serum troponin I levels was significantly higher in the patients with viral myocarditis than those in controls （P0.01）. These two variables were significantly negatively correlated （r=-0.3688,P0.05）. The RBC-ICRR levels were significantly higher in the patients than those in controls （P0.01） and were positively correlated with levels of cTnI （r=-0.3784,P0.05）. Conclusion There were disturbance of RBC immuno-regulation with suppressed immunofunction and higher cTnI levels in patients with viral myocarditis.

关 键 词：病毒性心肌炎 红细胞免疫功能 肌钙蛋白I 

分 类 号：R285.5[医药卫生—中药学]