EFFECTIVE DETECTION DEPTH OF NEEDLE-LIKE OPTICAL PROBE  

探针式光纤探头的有效检测深度(英文)

作　　者：李韪韬[1] 钱志余[1] 陈春晓[1] 肖笛[1] 

机构地区：[1]南京航空航天大学自动化学院

出　　处：《Transactions of Nanjing University of Aeronautics and Astronautics》2010年第1期76-80,共5页南京航空航天大学学报（英文版）

基　　金：Supported by the Natural Science Foundation of Jiangsu Province (BK2009371);the National High Technology Research and Development Program of China ("863" Program) (2008AA02Z438)~~

摘　　要：The effective detection depth of the needle-like optical probe is studied. The light transport model in highly scattering tissue is the diffusion equation and the boundary is Neuman. The sensitivity matrix is related to the position of the light source and the detector. It can be used to evaluate the effective detection depth. The sensitivity matrix is defined as the multiplication of the source and detector hght distribution. Six different groups about ix parameters including the source diameter and detector fibers, the core-to-core distance between the source and detector fibers, the opotode depth, the absorption, and reduced scattering coefficient, are used as experimental models. The relationship between the six parameters and the effective detection depth is analyzed. Resuits can be used to study the spatial resolution and the depth of multi-fibers.研究了探针式光纤探头的有效检测深度。采用扩散方程描述光在强散射生物组织中的传播规律,运用纽曼边界条件,使用灵敏度矩阵对有效检测深度进行了研究。灵敏度矩阵和光源与检测器的空间位置分布密切相关。光源与检测器对的灵敏度矩阵定义为:光源位置和检测器位置分别作为光源的光场分布的乘积。设计了6组针对不同参数的模型,参数主要包括光源、检测器光纤芯径、光源、检测器光纤中心距、光纤探头所处的深度、生物组织的吸收系数和散射系数。对探针式光纤探头在各组模型中的有效探测深度进行了仿真,重点研究了六种参数对检测深度的影响。所得结论可以推广到分析光纤检测器的空间分辨率和多光纤检测器的研究中。

关 键 词：probes optical fibers effective detection depth diffusion equation needle-like optical probe 

分 类 号：R445[医药卫生—影像医学与核医学] O43[医药卫生—诊断学]