沙枣叶水煎提取物体外抗氧化作用的研究  

Experimental Study on Anti-oxidant Effect of Extract from Leave of Elaeagnus Angustifolia L.in Vitro

作　　者：田卉[1] 刘彦军[1] 刘梅[2] 张梅[1] 马建慧[1] 

机构地区：[1]石河子大学药学院/新疆特种植物药资源重点实验室,石河子832002 [2]石河子大学医学院,石河子832002

出　　处：《石河子大学学报（自然科学版）》2010年第2期207-210,共4页Journal of Shihezi University(Natural Science)

摘　　要：本实验通过自发产生脂质过氧化及分别用自由基诱导剂CCl4、H2O2和Fe2+-VitC激发脂质过氧化,以丙二醛(MDA)产生量作为脂质过氧化作用程度指标,观察沙枣叶水煎提取物对小鼠肝脂质过氧化的保护作用强弱。结果显示沙枣叶水煎提取物可降低小鼠肝组织自发性MDA的生成,减轻CCl4、H2O2、Fe2+-VitC所诱导的肝脏脂质过氧化反应,具有良好的抗脂质过氧化作用。Lipoperoxidation model of rat liver was generated in liver homogenates spontaneously and induced by CCl4, H2O2 ,Fe^2＋-VitC. Concentration of malondialdehyde was measure. The results showed that the extracts from leave of Elaeagnus angustifolia L. inhibited the generation of MDA in rat live homogenates spontaneously formed and induced by CCl4, H2O2 and Fe^2＋-VitC. It alleviated injure from lipoperoxidation. The study indicated that extracts from leave of Elaeagnus angustifolia L. is effective on the inhibition of lipid peroxidation.

关 键 词：沙枣叶水煎提取物 脂质过氧化 丙二醛 

分 类 号：R966[医药卫生—药理学]