^(11)C-MET PET-CT显像对乳腺癌的诊断价值  

Clinical value of ^(11)C-MET PET-CT in diagnosis of breast cancer

作　　者：李善春[1] 朱世光[1] 徐志英[1] 谭桂萍[1] 王永涛[1] 江学文[1] 杨春凤[1] 

机构地区：[1]山东省烟台毓璜顶医院核医学科,山东烟台264000

出　　处：《医学影像学杂志》2010年第3期372-374,共3页Journal of Medical Imaging

摘　　要：目的:探讨11C-蛋氨酸(MET)PET-CT显像诊断原发性乳腺癌的临床应用价值。方法:因临床疑诊为原发性乳腺癌而行11C-METPET-CT显像的患者45例,显像后均行手术切除或穿刺活检。将PET-CT诊断结果与病理结果对照,分析11C-METPET-CT显像诊断乳腺癌的灵敏度和特异性。结果:以手术或活检病理结果为"金标准",11C-METPET-CT显像诊断乳腺癌的灵敏度、特异性和准确性分别为100%(44/44)、80%(12/15)、94.9%(56/69)。结论:11C-METPET-CT显像在乳腺癌早期准确诊断方面具有重要价值。Objective：The aim of this study was to evaluate the clinical role of 11C-methionine（MET） PET-CT in detection of breast cancer.Methods：11C-MET PET-CT scans were performed on 45 patients with suspected breast tumor.The final diagnosis was obtained by pathologic finding from surgery or biopsy.Results：The overall sensitivity,specificity and accuracy of 11C-MET PET-CT for detecting primary breast cancer were 100%（44/44）,80%（12/15） and 94.9%（56/59）,respectively.Conclusion：11C-MET PET-CT is a valuable imaging tool to early detect breast cancer.【

关 键 词：乳腺癌 体层摄影术 发射型计算机 蛋氨酸 

分 类 号：R814.42[医药卫生—影像医学与核医学] R737.9[医药卫生—放射医学]