冠心病合并2型糖尿病患者的脂代谢和冠状动脉造影分析  

A study of lipids and coronary angiography in type 2 diabetes with coronary heart disease

作　　者：刘婕[1] 马瑜瑾[1] 杨海燕[1] 滕中杰[1] 

机构地区：[1]河南科技大学第一附属医院内分泌科,河南省洛阳市471000

出　　处：《中国医药》2010年第5期397-398,共2页China Medicine

摘　　要：目的探讨冠状动脉粥样硬化性心脏病（冠心病）合并2型糖尿病患者的脂代谢和冠状动脉造影特点。方法选择经冠状动脉造影证实的冠心病患者310例，其中合并糖尿病患者106例，不合并糖尿病患者204例。比较2类患者的临床和冠状动脉造影资料。结果合并糖尿病的冠心病患者的TG、LDL—C水平较不合并糖尿病者明显升高，HDL—C水平明显下降[合并糖尿病者TG、LDL-C、HDL-C水平分别为（2．86±0．61）mmol／L、（3．42±0．53）mmol／L、（1．05±0．12）mmol／L；不合并者分别为（1．80±0．41）mmol／L、（2．74±0．21）mmol／L、（1．75±0．13）mmol／L]，差异有统计学意义（P〈0．05）。合并糖尿病的患者中，血脂异常者冠状动脉主要分支病变均增多。结论冠心病合并2型糖尿病患者的脂代谢明显紊乱，冠状动脉病变较为复杂。Objective To study the clinical and coronary angiographic characteristics in coronary heart disease （CHD） patients complicated with type 2 diabetes mellitus（DM）. Methods A total of 310 CHD patients confirmed by coronary angiography were divided two groups based on the concurrence with DM（ 105 patients） or not DM （204 patients）. Their clinical and coronary angiography results were analyzed. Results Compared with group with CHD, the level of TG and LDL-C obviously increased （P 〈0.05）and the level of HDL-C decreased in obserevation group （P 〈 0.05）. The DM patients suffered more from multi-vessel lesions. Conclusion Clinical and coronary angiographic characteristics are complicated in the patients with CHD and type 2 DM.

关 键 词：冠状动脉粥样硬化性心脏病 糖尿病 冠状动脉造影 

分 类 号：R541.4[医药卫生—心血管疾病]