急性创伤患者血清皮质醇和ACTH水平研究  

Study of serum corticosterone and ACTH levels in acute trauma patients.

作　　者：许兵[1] 王文霞[1] 徐卿[1] 吴蔚[1] 秦海军[1] 封启明[1] 

机构地区：[1]上海市第六人民医院急诊科,上海200233

出　　处：《海南医学》2010年第8期9-11,共3页Hainan Medical Journal

摘　　要：目的探讨急性创伤患者血清皮质醇和ACTH水平的变化特点。方法58例创伤病例通过创伤严重度评分(ISS)分为轻伤组(38例,ISS<16分)和重伤组(20例,ISS≥16分),伤后24 h内留取血标本,测定血清皮质醇和ACTH水平。结果重伤组24 h内血清皮质醇和ACTH水平均明显低于轻伤组(P<0.05)。结论在急性创伤患者中,肾上腺皮质功能不全有较高的发生率,测定伤后24 h内血清皮质醇水平有助于判断病情轻重。Objective To investigate the changes of serum corticosterone and ACTH levels in acute trauma patients. Methods 58 patients were divided into two groups according to the ISS scores： mild injury group（38 patients, ISS 〈16） and severe injury group（20 patients, ISS≥ 16）, serum corticosterone and ACTH levels were measured within 24 hours after injury. Results The serum corticosterone and ACTH levels in severe injury group were lower than those in mild injury group （P 〈 0.05 ）. Conclusion More acute trauma patients have adrenal insufficiency, the measurement of serum corticosterone and ACTH levels helps to judge the severity of trauma.

关 键 词：创伤 皮质醇 ACTH 肾上腺皮质功能不全 

分 类 号：R641[医药卫生—外科学]