胚胎移植后14～16日血清β-HCG值与早期妊娠结局的关系  

The relationship between serum β-HCG levels in 14～16 days after embryo transfer and early pregnancy outcome

作　　者：谭欣[1] 朱明辉[1] 贺贞[1] 杨丹[1] 

机构地区：[1]成都中医药大学第二临床医学院附属医院生殖中心,四川成都610041

出　　处：《中国计划生育和妇产科》2010年第2期10-12,共3页Chinese Journal of Family Planning & Gynecotokology

摘　　要：目的研究胚胎移植后14～16日血清人绒毛膜促性腺激素(β-human chorionic gonadotro-phin,β-HCG)值与辅助生殖技术(assisted reproductive techniques,ART)治疗后患者早期妊娠结局的关系。方法根据2006年11月至2009年10月在成都中医药大学第二临床医学院附属医院生殖中心行ART治疗胚胎移植后14～16日血清人绒毛膜促性腺激素β-HCG值阳性患者203例的妊娠结局(包括生化妊娠,宫外孕,临床妊娠早期流产,临床单胎妊娠及临床多胎妊娠)进行回顾性分析。结果①生化妊娠35例(17.24%);宫外孕12例(5.91%);临床妊娠早期流产13例(6.40%);临床单胎妊娠92例(45.32%);临床多胎妊娠51例(25.12%)。②早期妊娠不同结局分组间血清β-HCG值比较,差异有统计学意义(P<0.05),各组血清β-HCG值比较如下:临床妊娠双胎组>临床妊娠单胎组>临床妊娠流产组及宫外孕组>生化妊娠组;宫外孕组与临床妊娠组血清β-HCG值比较差异无统计学意义(P>0.05)。结论胚胎移植后14～16日血清β-HCG值能较好的预测ART治疗后早期妊娠结局。Objective To study the relationship between serum β-human chorionic gonadotrophin（β-HCG） levels in 14～16 days after embryo transfer and early pregnancy outcomes in patients with the treatment of assisted reproductive techniques（ART）. Methods The data resulting from the pregnancy outcomes of 203 patients with the treatment of assisted reproductive techniques（ART） and positive serum β-HCG levels in 14～16 days after embryo transfer from March 2007 to Oct. 2009 in Reproductive center,the second affiliated hospital of Chengdu traditional Chinese medical college in Chengdu city was analyzed retrospectively. Results There were 35 patients with biochemical pregnancy（17.24%）,12 patients with ectopic-pregnancy（5.91%）,13 patients with early abortion in clinical pregnancy （6.4%） and 92 patients with singleton in clinical pregnancy （46.31%） and 51 patients with multiple in clinical pregnancy （25.12%）. There was significant difference of the blood serum β-HCG levels among groups （P0.05） and the blood serum β-HCG levels in each group are as follows：the multiples in clinical pregnancy the singletons in clinical pregnancy early abortion and ectopicypregnancy biochemical pregnancy. But there was no difference of the blood serum β-HCG levels between the ectopic-pregnancy group and clinical pregnancy（P0.05）. Conclusion The blood serum β-HCG levels could make predication effectively in the early pregnancy outcomes after ART treatment.

关 键 词：血清人绒毛膜促性腺激素 妊娠结局 辅助生殖技术 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]