中药解毒活血方治疗颈动脉粥样硬化的对比观察  

TCM detoxicating and blood-activating therapy in the treatment of carotid atherosclerosis:Contrast observation

作　　者：李富玉[1] 许彦来[1] 李军艳[1] 张美增[2] 陈美南[1] 张少林[1] 

机构地区：[1]济南军区青岛第一疗养院,山东青岛266071 [2]青岛大学医学院附属医院,山东青岛266000

出　　处：《实用医药杂志》2010年第4期307-308,共2页Practical Journal of Medicine & Pharmacy

基　　金：青岛市科技专项(No.06224nsh)

摘　　要：目的分析解毒活血法对颈动脉粥样硬化(AS)患者高敏C反应蛋白(hs-CRP)、血清内皮素1(ET-1)及相关指标的影响。方法将60例颈AS患者,随机分为治疗组与对照组,连续用药12周,治疗组30例给予解毒活血方中药治疗,对照组30例给予辛伐他汀片治疗,分析两组患者hs-CRP、ET-1、胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的变化。结果两组治疗后hs-CRP、ET-1、TC、TG、HDL-C、LDL-C比较,有显著性差异(P<0.05或P<0.01)。结论说明解毒活血法能减轻炎性反应,调节血脂代谢,对动脉粥样硬化斑块有一定的消减和稳定作用。Objective To explore the effects of detoxicating and blood-activating therapy on the the levels of hs-CRP,ET-1 and related index of the patients with carotid atherosclerosis. Method The 60 patients with carotid atherosclerosis were divided into the treatment group and the control group randomly. The 30 cases in the treatment group were treated with detoxicating and blood-activating therapy, and the 30 cases in the control group were treated with Simvastatin tablets. Before and after 12 weeks of Continuous medication, hs-CRP, ET-i, TC, TG, HDL-C, LDL-C were measured. Result After the treatment, hs-CRP, ET-1, TC, TG, HDL-C, LDL-C were significantly different between the two groups （P〈0.05 or P〈0.01）. Conclusion＂ Detoxicating and blood-activating therapy can decrease and stabilize atherosclerotic plaque to some extent.

关 键 词：解毒活血法 中医疗法 颈动脉 粥样硬化斑块 

分 类 号：R543.5[医药卫生—心血管疾病]