牡丹皮多糖的含量测定  

Determination of polysaccharides content in Cortex Moutan

作　　者：于孟琦[1] 孙磊[1] 乔善义[1] 

机构地区：[1]军事医学科学院毒物药物研究所九室,北京100850

出　　处：《国际药学研究杂志》2010年第2期130-132,共3页Journal of International Pharmaceutical Research

基　　金：国家科技支撑计划(2006BAI08B03-08);国家科技重大专项资助项目(2009ZX09301-002)

摘　　要：目的测定牡丹皮多糖的含量。方法以精制牡丹皮多糖测得牡丹皮多糖对葡萄糖的换算因子,采用硫酸-苯酚法测定牡丹皮粗多糖的含量。结果牡丹皮粗多糖部位中多糖的含量为89.09%,生药中多糖的平均含量为7.54%,平均加样回收率101.22%。结论牡丹皮多糖的含量较高,为该药的进一步开发研究奠定了基础。Objective To determine the content of polysaccharides in Cortex Moutan.Methods The conversion coefficient of Cortex Moutan polysaccharides to glucose was obtained by refined polysaccharides,and then the content of polysaccharides in crude polysaccharides fraction was determined by sulfuric acid-phenol method.Results The content of polysaccharides in crude polysaccha-rides from Cortex Moutan was 89.09%,the average content of polysaccharides in Cortex Moutan was 7.54%,and the average recovery rate was 101.22%.Conclusion The content of polysaccharides in Cortex Moutan is comparatively high,which lays a foundation for the further research and development of Cortex Moutan.

关 键 词：牡丹皮 多糖 含量测定 

分 类 号：R284[医药卫生—中药学]