唾液酸酶法诊断细菌性阴道病的临床应用  

Clinic application of sialidase test in diagnosing bacterial vaginosis

作　　者：白桦[1] 林养[1] 吴春芳[1] 陈梅[1] 

机构地区：[1]湛江市第四人民医院,广东湛江524008

出　　处：《海南医学院学报》2010年第4期511-512,520,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020100136)~~

摘　　要：目的:探讨唾液酸酶法在诊断细菌性阴道病(bacterial vaginosis,BV)中的临床应用价值。方法:对475例疑似BV患者阴道分泌物分别采用常规镜检法、唾液酸酶法和Amsel法进行检测。结果:常规镜检法检查BV阳性数126例(26.5%),唾液酸酶法检出阳性数141例(29.7%),传统Amsel法检出阳性数124例(26.1%),唾液酸酶法与传统Amsel法相比较差异无统计学意义(P>0.05),具有较高的敏感性(92.7%)和特异性(92.6%);当合并白假丝酵母菌和滴虫感染时,其病原体对唾液酸酶活性检测未产生显著影响。结论:唾液酸酶测定是BV诊断的一项较为灵敏的有效方法,可显著提高BV的诊断率。Objective：To investigate the clinic value of sialidase test in diagnosing bacterial vaginosis（BV）.Methods：Tested vaginal secretion of 475 suspecious BV cases with conventional microscopy,sialidase test and Amsel method.Results：One hundred and twenty six cases with PV positive were detective by conventional microscopy（26.5%）,141 cases by sialidase test（29.7%）,abd 124 by Amsel method（26.1%）.There was no significant difference between sialidase test and Amsel method（P〉0.05）.And sialidase test was of high sensitivity（92.7%）and specifility（92.6%）.The complication of infection of candida vagitis and trichomonas showed no marked effect of the activity of sialidase test.Conclusion：Sialidase test is effective diagnosis method for BV,and can obviousliy increase the diagnosis rate.

关 键 词：细菌性阴道病 唾液酸酶法 常规镜检法 AMSEL法 

分 类 号：R711.31[医药卫生—妇产科学]