心肌肽素对大鼠急性心肌缺血的保护作用  

Protective Effect of Cardiomyopeptidi on Acute Myocardial Ischemia in Rats

作　　者：赵强[1,2] 

机构地区：[1]吉林大学,吉林长春130000 [2]内蒙古民族大学附属医院,内蒙古通辽028000

出　　处：《内蒙古民族大学学报（自然科学版）》2010年第2期197-199,共3页Journal of Inner Mongolia Minzu University：Natural Sciences

摘　　要：目的:观察心肌肽素(cardiomyopeptidi)对大鼠急性心肌缺血的保护作用.方法:建立垂体后叶素(Nh)致急性心肌缺血及冠状动脉结扎致急性心肌梗死模型,采用心电图机测定心肌肽素对大鼠Ⅱ导联及胸V1导联心电图变化的影响.结果:心肌肽素50μg/ml对Nh诱发大鼠心电图T波及ST段的抬高有明显降低作用,亦能明显改善冠状动脉结扎致心肌梗死不同时间点的缺血性心电图变化.结论:心肌肽素对实验性心肌缺血大鼠心电图有明显改善作用.Objective：To observe the protective effect of cardiomyopeptidi on acute myocardial ischemia in rats. Methods：Acute myocardial ischemia models were induced by neurohypophyseal hormone（Nh） and myocardial infarction models were caused by ligating coronary artery,the effect of cardiomyopeptidi on ECG in acute myocardial ischemia rats was observed. Results：Cardiomyopeptidi could reduce the heights of ST segment and T wave which caused by injecting Nh and ligating coronary artery. Conclusion：Cardiomyopeptidi can obviously improve the ECG of rats with acute myocardial ischemia.

关 键 词：心肌肽素 心肌缺血 心肌梗死 

分 类 号：R331.3[医药卫生—人体生理学] R332[医药卫生—基础医学]