尿路感染病人尿培养检出病原菌及其耐药情况分析  

Urine culture of urinary tract infection patients and the drug resistance status analysis

作　　者：李俭 李锦玲 罗素华 方晓霞[2] 陈维媚[2] 蒋素莹[2] 

机构地区：[1]福建省连城县医院检验科,福建连城366200 [2]福建省龙岩市第一医院检验科,福建龙岩364000

出　　处：《世界感染杂志》2010年第1期35-38,共4页World Journal of Infection

摘　　要：目的了解我院门诊与住院治疗泌尿系感染病人病原菌分布及其对常用抗菌药物的耐药情况，为临床合理应用抗生素提供依据。方法收集我院2005～2007年门诊及住院泌尿系感染病人尿培养检测的病原菌，采用Vitek32细菌分析系统进行鉴定和药敏试验。结果2005年1月至2007年12月共检出869株病原菌中，革兰阳性菌224株（25．78％），革兰阴性菌645株（74．22％）。检出病原菌前5位的依次为大肠埃希菌431株（49．60％），真菌91株（10．48％），肺炎克雷伯菌80株（9．21％），葡萄球菌属61株（7．02％），肠球菌属61株（7．02％）。还有的病原菌依次为铜绿假单胞菌31株（3．57％），奇异变形杆菌25株（2．88％），阴沟肠杆菌21株（2．42％），醋酸钙不动杆菌19株（2．19％）。其它菌49株（5．61％），除真菌外革兰阳性菌对万古霉素最敏感，革兰阴性菌较敏感药物为亚胺培南。结论临床应根据药敏试验结果合理选用抗菌药物。Objective To investigate the out-patient clinic and inpatient care patients＇ pathogenic bacteria distribution of urinary tract infection and the drug resistance status, and provide the basis for the reasonable administration of antibiotics. Methods Collect the pathogenic bacteria of urinary tract infection patients between 2005 and 2007, and use the Vitek32 bacterium analytical system to identify and test susceptibility. Results Out of 869 pathogenic bacteria between January 2005 and December 2007, 224 cases were Gram-positive （25.78%）, 645 were Gram-negative （74.22%）. 431 were Escherichia coli （49.60%）, 91 were true fungus （10.48%）, 80 were Klebsiella pneumoniae （9.21%）, 61 were staphylococci （7.02%）, 61 were enterococci （7.02%）, 31 were Pseudomonas aeruginosa （3.57%）, 25 were Proteus mirabilis （2.88%）, 21 were Enterobacter cloacae （2.42%）, 19 were Acinetobacter calcoaceticus （2.19%）. Gram-positive bacteria were sensitive to vancomycin, Gram-negative bacteria were sensitive to imipenem. Conclusions Antibacterials should be chosen according to the susceptibility test results.

关 键 词：泌尿系感染 病原菌 耐药 

分 类 号：R691.3[医药卫生—泌尿科学]