24式简化太极拳对2型糖尿病患者血清炎性细胞因子及生活质量的影响  

Tai chi for the treatment of type 2 diabetes

作　　者：吴凡[1] 宋恩峰[1] 包艳[2] 向建武[3] 贾汝汉[4] 

机构地区：[1]武汉大学人民医院中西结合科,武汉430060 [2]武汉大学人民医院内分泌科,武汉430060 [3]武汉大学人民医院康复医学科,武汉430060 [4]武汉大学人民医院肾脏病科,武汉430060

出　　处：《中华物理医学与康复杂志》2010年第3期205-207,共3页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：目的观察太极拳对2型糖尿病患者细胞因子水平和生活质量的影响。方法将糖尿病患者40例随机分为太极拳组与对照组，治疗前、后进行白细胞介素-6（IL-6）、白细胞介素-18（IL—18）、白细胞分化抗原CD40配体（sCD40L）、超敏C反应蛋白（hsCRP）及相关生化指标测定，并用SF-36量表对患者的生活质量进行评估。结果太极拳组血糖、胰岛素水平明显下降，IL-6、IL．18、sCD40L、hsCRP表达明显下调，生存质量明显提高，与其治疗前和对照组治疗后比较差异有统计学意义（P〈0．05）。结论太极拳通过下调炎性细胞因子表达，减轻对胰岛细胞的损害，提高了机体对胰岛素的敏感性，改善了胰岛素抵抗状态，延缓了糖尿病并发症的发生，提高了2型糖尿病患者的生活质量。Objective To determine the effects of practicing a simplified 24 movement form of Tai chi on the level of inflammatory cytokines and the quality of life of type 2 diabetes patients. Methods A group of type 2 diabetes patients practiced a simplified 24 movement Tai ebi routine 60 rain/d, 3 d/week for 6 months. Plasma glucose and insulin concentration were monitored. The plasma level of IL-6, IL-18, sCD40L, hsCRP and HBAel were measured. Changes in the patients＇ quality of life were also measured by using the SF-36. Results Serum IL-6, IL-18, hsCRP and sCD40L levels were all significantly lower compared with a control group. Significant quality of life improvements were seen in the Tai chi group compared with the controls. Significant reductions were seen in blood pressure, glycated haemoglobin, glucose, insulin resistance and urinary albumin. Conclusions These results suggest that regular Tai chi practice can prevent complications and improve the quality of life of diabetes sufferers through glycaemic control and down-regulating inflammatory eytokine levels.

关 键 词：太极拳 糖尿病 氧化应激 生活质量 

分 类 号：R587.1[医药卫生—内分泌]