黄牡固本丸质量标准的初步研究  

Studies on quality standard of Huangmuguben Pills

作　　者：萧绮珊 林艳云[2] 何玉英 

机构地区：[1]广东省中山市药品检验所,528437 [2]南方医科大学附属中山市博爱医院 [3]广州市海珠区妇幼保健院

出　　处：《中国实用医药》2010年第12期11-12,共2页China Practical Medicine

摘　　要：目的对黄牡固本丸建立有效的质量控制方法。方法采用薄层色谱法对白术、牡丹皮、大黄、淫羊藿进行定性色谱鉴别;采用薄层色谱扫描法测定了方中黄芪所含黄芪甲苷的含量。结果该方法专属性强,含量测定黄芪甲苷在0.54～4.32μg间呈现良好的线性关系,黄芪甲苷平均回收率为97.11%,RSD=1.35%;薄层色谱鉴别斑点清晰,无干扰,易分辨。结论该法准确、简便、重复性好,可用于黄牡固本丸的质量控制。Objective To establish the effective quality control standard of Huangmuguben Pills.MethodsBy TLC right for Rhizoma Atractylodis Macrocephalae,Cortex Moutan,Radix et Rhixoma Rhei and Herba Epimedii identification by qualitative.Astragaloside Ⅳ in Huangmuguben Pills was determined by TLC-Scanning.ResultsThe calibraction curve was linear in the range of 0.54~4.32 μg,the average recovery was 97.11%,RSD=1.35%;the chromatographic spots wer clear,without interference and easy to recognize.ConclusionThe method is accurate,simple and reproducible.It could be used for the quality control of Huangmuguben Pills.

关 键 词：黄牡固本丸 质量标准 黄芪甲苷 薄层扫描法 

分 类 号：R286[医药卫生—中药学]