压迫间隔时间与皮肤压疮形成关系的实验研究  

Experimental research on the relationship between the oppression time interval and the formation of pressure Ulcers

作　　者：庄嘉元[1] 姜小鹰[1] 宋继红[1] 

机构地区：[1]福建医科大学护理学院,福州350004

出　　处：《中华现代护理杂志》2010年第4期373-376,共4页Chinese Journal of Modern Nursing

基　　金：福建省2009年自然基金项目支持（2009J01151）

摘　　要：目的通过压迫间隔时间与皮肤压疮形成之间关系的实验研究，探讨压疮预防中合理、有效的翻身间隔时间。方法制备104只SD大鼠受压模型，将其随机分为对照组48只、实验组56只，对照组压迫2h后放松2h，实验组逐步延长压迫间隔时间，并根据受压时间的不同将两组再分为各个不同的亚组，比较两组不同观察时间的病理学指标改变。结果各组均未出现肉眼可见的皮肤破损等严重的变化，但在皮肤发红率、中性粒细胞浸润程度、肥大细胞聚集及肥大细胞脱颗粒率方面，实验组均小于对照组，差异有统计学意义（P〈0．05）。结论逐步延长压迫间隔时间的方法能减轻组织损伤，可为临床压疮预防护理研究提供一定的理论依据。Objective Objective： Studying on the relationship between the oppression time interval and the formation of pressure deers so as to research the reasonable and effectual turn over time interval. Methods Establishing the SD rats pressure ulcer animal models, under visual observation and pathological observation in order to study the rat skin tissues injury situations by differentiating the same oppression time interval method and the gradually extending oppression lime interval method. Results Each group had no visible skin damages and other serious changes, but the comparison differences between the control group and the experimental group in the aspects of redness, neutrophil infiltration degree, mast cell aggregation, and mast cell deregulation rats were statistically significant （P 〈 0. 05）. Conclusions Under these experimental conditions, the oppression method of gradually extending the time interval can reduce tissue injury.The results of this study may in the future provide clinical nursing intervention in the implementation of certain theoretical support.

关 键 词：压疮 预防 实验 皮肤护理 

分 类 号：R473[医药卫生—护理学]