再生障碍性贫血血清及红细胞内锌含量的研究  

A STUDY ON THE CONTENT OF ZINC IN SERUM AND ERYTHROCYTES IN APLASTIC ANEMIA

作　　者：徐开林[1] 贾兆通[1] 翁维权[1] 张春源[1] 

机构地区：[1]青岛医学院附院内科

出　　处：《青岛医学院学报》1990年第2期136-13,共1页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：用原子吸收分光光度法测定了48例再生障碍性贫血(再障)患者血清及红细胞内锌的含量.血清锌含量明显低于正常人(P<0.01),红细胞内锌含量高于正常人(P<0.05),血清锌与红细胞锌呈负相关(r为-0.532,P<0.01).病情缓解时,红细胞内锌含量接近正常,红细胞内锌含量变化出现于骨髓变化的同时或之后,血象尚无明显变化之前.结果提示:再障时,血液成分中锌分布异常,红细胞锌水平对估计再障病情变化可能有一定帮助.Zinc content of serum and erythrocytes of 45 normal subjects and 48 patients With aplastic anemia (AA) was measured by atomic absorption spectrophotometry. The zinc content of serum in patients with aplastic anemia was significantly decreased and that of erythrocytes was increased as compared to normal controls. An inverse correlation was observed between the serum zinc content and the erythrocyte zinc content in AA patients. The mechanism and clinical significance of the changes in zinc content in AA patients are discussed.

关 键 词：再生障碍性 血清 红细胞 锌 贫血 

分 类 号：R556.5[医药卫生—血液循环系统疾病]