中药退黄外洗液质量标准研究  

Quality Standard of Jaundice-abating Chinese Herbal Lotion for External Use

作　　者：黄仕孙[1] 王艳宁[1] 高桂娥[1] 余莉玲[1] 吴曙粤[1] 张涛 岑淑姬 陈学松 

机构地区：[1]南宁市第一人民医院,南宁市530022 [2]广西梧州市食品药品检验所,梧州市543002

出　　处：《中国药房》2010年第15期1399-1400,共2页China Pharmacy

基　　金：广西科学基金项目(桂科自0832278);南宁市科学研究与技术开发计划项目(20040246C)

摘　　要：目的:建立中药退黄外洗液的质量标准。方法:采用薄层色谱(TLC)法对方中大黄、薄荷脑进行定性鉴别;采用高效液相色谱(HPLC)法对制剂中栀子苷进行含量测定。结果:TLC斑点清晰,分离度好、专属性强。栀子苷进样浓度在5.46～81.9μg.mL-1范围内与峰面积积分值呈良好线性关系(r=0.9998);平均回收率为98.38%,RSD=1.53%(n=6)。结论:所建标准可用于中药退黄外洗液的质量控制。OBJECTIVE：To establish the quality standard of Jaundice-abating Chinese herbal lotion for external use. METHODS：The component Rheum officinale and menthol were qualitatively identified by TLC,and the content of jasminoidin in formulation was determined by HPLC. RESULTS：The TLC spots were clear,well-separated and specific. The linear range of jasminoidin was 5.46～81.9μg·mL-1（r=0.999 8） with an average recovery of 98.38%（RSD=1.53%,n=6）. CONCLUSION：Established quality standard can be used for the quality control of Jaundice-abating Chinese herbal lotion for external use

关 键 词：中药退黄外洗液 质量标准 薄层色谱法 高效液相色谱法 

分 类 号：R283.61[医药卫生—中药学] R927.1[医药卫生—中医学]