居泉沙雷菌与褪色沙雷菌分布及耐药性对比分析  

Distribution and Drug Resistance of Serratia fonticola and Serratia marcescens:A Comparative Analysis

作　　者：来汉江[1] 杨莉俊[1] 顾保罗[1] 周鸿亮[1] 陈小静[1] 

机构地区：[1]杭州萧山第一人民医院检验科,浙江杭州311201

出　　处：《中华医院感染学杂志》2010年第7期1020-1022,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解居泉沙雷菌与褪色沙雷菌感染的分布及耐药特点,为临床治疗提供参考。方法对18株居泉沙雷菌与28株褪色沙雷菌进行回顾性分析。结果52株沙雷菌属中有居泉沙雷菌18株(34.62%)分离主要来自泌尿道(44.44%),褪色沙雷菌28株(53.85%)分离主要来自呼吸道(92.86%);两者药敏结果对头孢菌素、氨基糖苷类耐药率高,对亚胺培南、哌拉西林/他唑巴坦、厄他培南的耐药率一致且较低,经2χ检验显示氨曲南、环丙沙星、左氧氟沙星、呋喃妥因的抗菌活性差异有统计学意义。结论居泉沙雷菌和褪色沙雷菌的耐药性严重,有差异,不同细菌的耐药性的统计分析临床意义较大,有利于对"菌"下药。OBJECTIVE The understand the distribution and resistance characteristic of Serratia fonticola and S. rnarcescens infection, and provide the reference for the clinical care. METHODS Eighteen S. fonticola strains and 28 S. marcescens strains were retrospectively analyzed. RESULTS From totally 52 Serratia strains 18 （34.62%） S. fonticola strains were mainly isolated from the urinary tract （44.44%） , and 28 （53.85%） strains S. marcescens mainly were from respiratory tract （92. 86%）. Both had higher resistance to the cephalosporins and aminoglycosides and lower to the imipenem, piperacillin/tazobactam. According to Chi-square test it was demonstrated that the antibacterial activity of aztreonam, ciprofloxacin, levofloxacin and nitrofurantoin had significant differrence. CONCLUSIONS The S. fonticola and S. rnarcescens have serious but different drug resistance, which can he in favor of antibacterial treatment.

关 键 词：沙雷菌属 分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]