肺表面活性物质联合经鼻气道正压通气预防呼吸窘迫综合征  

Clinical study on prewenting NRDS in very low birth weight infant with pulmonary surfactant and nasal postitive airway pressure

作　　者：何中倩 李晓东 刘丽芳 

机构地区：[1]深圳南山区人民医院新生儿科,广东518052

出　　处：《中国优生与遗传杂志》2010年第4期109-110,37,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的为探讨肺表面活性物质联合经鼻气道正压通气对极低出生体重儿NRDS的预防价值。方法将2005年1月至2008年12月期间收住我科的极低出生体重儿73例按是否早期使用PS分为预防组(30例)及对照组(40例),比较其NRDS的发病率及存活率。结果预防组的NRDS及并发症的发生率较对照组明显降低(P<0.05)。结论早期使用PS并联合经鼻气道正压通气可有效预防极低出生体重儿的NRDS的发病率,并改善NRDS的治疗效果。Objective：To evaluate the benefical effectiveness of pulmonary surfactant （PS） and Nasal positive airway pressure on prevention of NRDS in very low birth weight infant.Methods：A total of 73cases of very low birth weight infants were randomly divided to Pulmonary surfactants group （n=30） and the blank control group（n=43） between January 2005 and December 2008.Results：The proportion of NRDS and complications were signinficantly shorter than the contrasted group（P0.05）.Conclusion：The therapy prevented for very low birth weight infant by pulmonary surfactant may reduce the proportion of NRDS and improve clinical effeteness of very birth weight infant singnificantly.

关 键 词：肺表面活性物质 经鼻气道正压通气 极低出生体重儿 新生儿呼吸窘迫综合征 

分 类 号：R722.1[医药卫生—儿科]