辅助生殖技术后发生宫内外同时妊娠的相关因素分析  

Analysis of the factors of heterotopic pregnancy after ART

作　　者：刘风华[1] 李旎[1] 

机构地区：[1]广州医学院第三附属医院生殖助孕科,广州510150

出　　处：《中国优生与遗传杂志》2010年第4期126-127,131,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨辅助生殖技术后发生宫内外同时妊娠的高危因素、诊断、治疗及预后。方法对2005年1月～2008年10在广州医学院第三附属医院生殖科进行辅助生殖治疗后发生的7例宫内外同时妊娠病例进行回顾性分析。结果宫内外妊娠的发生率为0.6%,5例为输卵管因素不孕,其中1例有既往异位妊娠史。6例经B超确诊,1例经手术确诊。1例行阴道B超引导下异位孕囊穿刺抽吸胚芽术,1例行输卵管切开取胚术,5例行输卵管切除术,其中3例在异位病灶去除后继续宫内妊娠并分娩活婴。结论既往输卵管盆腔疾病或手术、异位妊娠史是辅助生殖技术后发生宫内外同时妊娠的高危因素。对有高危因素的患者早期加强B超检测有助于早期诊断、早期治疗,将对宫内妊娠的影响减到最小。Objective：To explore the risk factors,diagnosis,treatment methods and prognosis of heterotopic pregnancy （HP） after ART.Methods：We retrospectively analysed the clinical data of 7 patients with HP after ART conducted in from January 2005 to October 2008.Results：The incidence of HP was 0.6 %.Among all heterotopic pregnancies,the assisted conception of 5 cases were tubal factor.One of them had history of ectopic pregnancy.Six of them were diagnosed by transvaginal ultrasonography detection.One patient was diagnosed in the surgical procedure.One patient was treated by transvaginal utrosonographic guidance ectopic gestational sac aspiration.One patient was suffered from salpingotomy and 5 patients were suffered from salpingectomy.3 patients of the complicated gestation produced live children.Conclusions：Patients with tubal or pelvic diseases,surgerys and history of ectopic pregnancy are high risk factors of HP after ART.Close monitoring by B -ultrasound in the early weeks of pregnancy to the patients who with high risk of HP help to early diagnosis and treament.The harmful effects on the intrauterine embryo will be maximally decreased by early diagnosis and treatment of HP.

关 键 词：辅助生殖技术 宫内外同时妊娠 妊娠结局 

分 类 号：R711.6[医药卫生—妇产科学] R714.8[医药卫生—临床医学]