N,N’-二甲基-4-氨基吡啶的合成及应用  

Synthesis and Application of N，N’-Dimethyl-4-Aminopyridine

作　　者：郑嗣华[1] 施志荣[2] 张嘉琪[1] 李国珍 

机构地区：[1]天津理工学院,天津300191 [2]天津师范大学,天津300074

出　　处：《天津理工学院学报》1998年第a07期26-28,共3页Journal of Tianjin Institute of Technology

摘　　要：以廉价的吡啶为主要原料，通过联吡啶盐中间步骤合成高效酰化催化剂N，N-二甲基-4-氨基吡啶，并对产物的结构进行了FTIR认证．用GLC跟踪测试高位阻叔丁醇的酰化反应，结果表明：该催化剂具有很高的催化活性，3h叔丁醇转化率可达93％．Abstratt: N,N-Dimethyl-4-aminopyridine, as a highly effeicient acylarion catalyst. was synthesized by a conveniently twostep approach. That is, first, N-(4-pridinyl)pyridinate chloride salt (dipyridine salt) was prepared by treatment of 4-aminopyridine with SOCl_2, Second, DMAP was obtained by means of the reaction involving dipyridine salt and dimethylamine and was identified with FTIR. Then, acylation of tert-butanol (an acylation of high steric hindrance tritiary alcohol) was catalyzed by this substance and the catalytic activity of the DMAP was tested in terms of acetylation monitored by gas chromatography.

关 键 词：氨基吡啶 酰化反应 叔丁醇 催化剂 DMAP 合成 

分 类 号：O626.32[理学—有机化学] O621.256.1[理学—化学]