中药汽雾透皮疗法治疗原发性纤维肌痛综合征前瞻性临床初步研究  

Vapor-mist diacutis therapy of traditional Chinese medicine treatment for fibromyalgia syndrome:a prospective,open labeled clinical trial

作　　者：刘建忠[1] 刘艳芳[1] 吴江亭 王小磊[1] 谭举朋[1] 杜海莲[1] 

机构地区：[1]潍坊市益都中心医院风湿科,山东省262500

出　　处：《中华临床医师杂志（电子版）》2010年第4期56-59,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的评价中药汽雾透皮疗法治疗纤维肌痛综合征(FMS)的临床疗效和安全性。方法将132例患者随机分为对照组、汽疗组和联合组,三组均以心理干预为基础治疗,同时对照组服阿米替林治疗,汽疗组采用中药汽雾透皮疗法治疗,联合组采用中药汽雾透皮疗法和阿米替林联合治疗,三组在治疗4周、12周时以简化麦吉尔疼痛问卷(SFMPQ)、汉密尔顿抑郁量表(HAMD)、纤维肌痛影响问卷(FIQ)和压痛点计数评估疗效,同时观察记录不良反应。结果三组治疗后SFMPQ中的所有分项得分、HAMD评分、FIQ总分较治疗前均有不同程度的改善(P<0.01),且联合组和汽疗组较对照组改善明显,差异有统计学意义(P<0.05,P<0.01);汽疗组和联合组压痛点计数较治疗前显著减少(P<0.01),而对照组无变化(P>0.05);同组治疗12周与4周时比较,SFMPQ中的所有分项得分、HAMD评分、FIQ总分及压痛点计数差异均无统计学意义(P>0.05)。不良反应发生率汽疗组小于对照组(P<0.01),联合组与对照组比较差异无统计学意义(P>0.05)。结论中药汽雾透皮疗法可以有效治疗FMS,疗效与安全性优于阿米替林,二者联合可以显著提高疗效。Objective To evaluate the clinical therapeutic effect and security of vapor-mist diacutis therapy of traditional Chinese medicine in the treatment of fibromyalgia syndrome （FMS）. Methods 132 patients were divided into control group,vapor therapy group and combination group at random.The control group was treated with amitriptyline,the vapor therapy group was treated with vapor-mist diacutis therapy of traditional Chinese medicine and the two therapies were applied in combination group with mental intervention as foundation treatment in all groups.The clinical therapeutic effect were evaluated with SFMPQ,HAMD,FIQ and counting of tenderness point when the treatments were undertaken for 4 weeks and 12 weeks in 3 groups,and the adverse effect were observed and recorded at the same time. Results All of the sub item score in SFMPQ,HAMD score and FIQ score were improved with unequal degree after the treatment in 3 groups （P〈0.01）,furthermore,the improvement in vapor therapy group and combination group were more obvious than in control group,with the difference had significance（P〈0.05,0.01）;counting of tenderness point decreased predominantly in vapor therapy group and combination group （P〈0.01）while there was no variation in control group（P〉0.05）;the difference of 4 weeks and 12 weeks of treatment in all of the sub item score in SFMPQ,HAMD score,FIQ score and counting of tenderness point had no significance（P〉0.05）.Incidence rate of adverse effect of vapor therapy group was less than control group（P〈0.01）,the difference of control group and combination group had no significance（P〉0.05）. Conclusions Vapor-mist diacutis therapy of traditional Chinese medicine can treat fibromyalgia syndrome effectively with better clinical therapeutic effect and security than amitriptyline,and clinical therapeutic effect can be boosted predominantly when they are combined.

关 键 词：纤维肌痛 中药离子透入 治疗结果 

分 类 号：R274[医药卫生—中医骨伤科学]