不同原因所致早产儿的临床特征  

Clinical Features of Preterm Infants Induced by Different Reasons

作　　者：徐发林[1] 别静洋[1] 

机构地区：[1]郑州大学第三附属医院新生儿科,郑州450052

出　　处：《实用儿科临床杂志》2010年第8期582-583,共2页Journal of Applied Clinical Pediatrics

基　　金：河南省医学科技攻关项目(200803065)

摘　　要：目的比较不同原因所致早产儿的临床特征,为早产儿分类管理、合理诊治提供依据。方法对2008年12月-2009年6月在郑州大学第三附属医院NICU住院的存在胎膜早破、妊娠高血压综合征、胎盘早剥的孕妇所分娩238例活产早产儿的一般情况和临床特征进行对比,其中胎膜早破组99例,妊娠高血压综合征组89例,胎盘早剥组50例。结果3组早产儿在胎龄、双胎比例、病死率方面比较均无统计学差异(Pa>0.05)。妊娠高血压综合征组早产儿出生体质量较低。胎膜早破组早产儿窒息发生率较低(P<0.05)。胎膜早破组CRP阳性率较高,住院天数最短,与其他2组比较均有统计学差异(Pa<0.05);胎膜早破组呼吸窘迫综合征发生率低于妊娠高血压综合征组和胎盘早剥组,但均无统计学差异(Pa>0.05)。胎盘早剥组凝血异常发生率较高,与其他2组比较有统计学差异(Pa<0.05)。结论不同原因所致早产儿临床特征存在差异,应结合导致早产的病因进行分类管理。对胎膜早破所致早产儿应加强感染方面的管理,对妊娠高血压综合征、胎盘早剥所致早产儿应重视营养支持、窒息及凝血功能检测。Objective For the purpose of assort management and rational treatment of premature babies,the clinical features of preterm infants with different reasons were analyzed.Methods The clinical features of 238 preterm babies admitted to NICU from Dec.2008 to Jun.2009 were analyzed.Among them,99 cases were related with premature rupture of membrane （PROM group）,89 cases were from pregnancy induced hypertensive syndrome（PIH group）,and 50 cases had placental abruption（placental abruption group）.Results No significant difference was found among the 3 groups with regard to gestational age,mortality rate and the ratio of twins（Pa0.05）.The birth weight in PIH group and the asphyxia incidence rate in PROM group were lower than those in the other groups（P0.05）.The ratio of C-reactive protein positive reaction was higher,but hospital stay was shorter in the PROM group compared with those in other groups（Pa0.05）.The incidence of respiratory distress syndrome was not different among the groups（Pa0.05）.However,the incidence of abnormal cruor was significantly higher in the placental abruption group than that in other groups（Pa0.05）.Conclusions The clinical features were different in the premature babies for different reasons and management should be different accordingly.For the preterm infants related to PROM,it is important to put emphasis on the management of infection.For the preterm infants resulting from PIH and placental abruption,nutrition support is critical,as well as the asphyxia and the inspection of cruor function.

关 键 词：胎膜早破 妊娠高血压综合征 胎盘早剥 临床特征 婴儿 早产 

分 类 号：R722.6[医药卫生—儿科]