老年人不同亚型轻度认知功能损害调查  

Incidence of mild cognitive impairment and its subtypes among the elderly in communities of Guiyang city

作　　者：蔡毅媛[1] 黄文湧[1] 杨敬源[1] 杨星[1] 汪俊华[1] 韦继芳[1] 

机构地区：[1]贵阳医学院公共卫生学院流行病学教研室,贵阳550004

出　　处：《中国公共卫生》2010年第4期403-405,共3页Chinese Journal of Public Health

基　　金：国家自然科学基金(30860245);贵州省省长资金项目(黔省专合字[2007]47);贵州省科技攻关项目(黔科合S字[2007]1042);贵阳市科技项目(建筑合字[2008]8-5)

摘　　要：目的了解贵州省贵阳市城区≥60岁,老年人轻度认知功能损害(MCI)及其不同亚型的发病情况。方法通过问卷询问和量表测试,对贵阳市城区2 200名≥60岁认知正常老年人进行随访研究,运用简易智能状态检查量表(MMSE)进行认知功能评定,研究对象的一般情况描述及比较采用χ2检验和u检验。结果贵阳市城区老年人MCI的发病密度为15.6/1 000人年;遗忘型MCI的发病密度为11.0/1 000人年,无遗忘型-单领域型发生,所有遗忘型MCI均为多领域型;非遗忘型MCI的发病率为4.6/1 000人年,其单领域型和多领域型的发病密度为0.4/1 000人年和4.2/1 000人年;女性、文盲发生非遗忘型MCI较多(P<0.05)。结论不同亚型的发病情况有差别,不同特征人群的发病分布情况也不同。Objective To investigate the incidece of mild cognitive impairment（MCI） and its subtypes among the elderly in communities of Guiyang city.Methods A follow-up study was conducted among 2 200 persons aged 60 years and over with normal cognitive function.The cognitive function of the subjects was asessed with mini-mental state examination（MMSE）.The general condition of the subjects was described and the incidences of MCI among different sub-population were compared with Chi-square test and u test.Results Among the subjects,the incidence of MCI was 15.6/1 000 perosn years and amnestic MCI was 11.0/1 000 person years.There was no amnestic MCI-single domain observed.The incidence of amnestic MCI-multiple domain,non-amestic MCI,non-amnestic MCI-single domain,and non-amnestic-multiple domain was 11.0,4.6,0.4,and 4.2/1 000 person years,respectively.The incidence of amnestic MCI was higher than that of non-amnestic MCI.The incidence of multiple domains＇ subtype was higher than that of single domain.The female had a higher incidence than male in non-amnestic MCI.The illiterates had a higher incidence than others in non-amnestic MCI（P0.05）.Conclusion The incidence of MCI subtypes is different.The incidence of MCI is different in sub-populations.

关 键 词：老年人 轻度认知功能损害 发病密度 不同亚型 

分 类 号：R195[医药卫生—卫生统计学]