二水杨醛三乙基四胺合钴(Ⅲ)金属配合物的合成  

The Synthesis of the Metal Complex [Co(Sal_2trien)]Cl

作　　者：周成勇[1] 李伟[1] 

机构地区：[1]长治学院生化系,山西长治046011

出　　处：《长治学院学报》2009年第5期7-9,共3页Journal of Changzhi University

摘　　要：多胺类金属配合物在调控特定基因表达方面具有巨大潜力,而钴(Co)是维生素B12的组成成分,是一种独特的营养物质,被列为人体必需的微量元素之一。文章以水杨醛、三乙基四胺和CoCl3?6H2O合成了二水杨醛三乙基四胺合钴(Ⅲ)金属配合物,并通过熔点和电导率的测定初步推断了其可能的结构,以期进一步研究该小分子金属配合物与DNA的相互作用,从而为其在药物的开发和分子生物学中的应用提供有价值的信息。Polyamines have enormous potential in the regulation of specific gene expression.Moreover cobalt（Co）is the composition of vitamin B12 and a unique nutrient substance,trace elements as essential in human body.Therefore,in this paper,the Co（Ⅲ）metal complex with salicylaldehyde dihydrate triethyltetramine has been synthesized,and its possible structure has been inferred through the determination of its melting point and electrical conductivity.The purpose is to provide valuable information for exploiting and developing drugs and their application in the field of molecular biology through to further study the interaction of it and DNA.

关 键 词：水杨醛 三乙基四胺 钴金属配合物 

分 类 号：O622.4[理学—有机化学]