大鼠“延髓内脏带”内SP受体的分布及其形态学特征  

DISTRIBUTION AND MORPHOLOGICAL FEATURE OF SPR IN “MEDULLARY VISCERAL ZONE” OF RAT

作　　者：高文 刘惠玲[1] 饶志仁[1] 

机构地区：[1]第四军医大学神经科学研究所

出　　处：《解剖学报》1998年第2期165-169,I012,I013,共7页Acta Anatomica Sinica

摘　　要：为了探讨ＳＰ受体（ＳＰＲ）阳性结构在大鼠延髓内脏带（ＭＶＺ）的分布和形态学特征及其与ＴＨ阳性神经元的关系，用免疫组织化学方法系统观察了大鼠延髓。结果表明，大鼠ＭＶＺ有较密集的ＳＰＲ样阳性结构分布，与ＳＰ样阳性结构的分布基本一致。ＳＰＲ样阳性胞体与纤维染色有浓有淡，胞体大小、形态各异，纤维大体分为３类，即羊毛型、光滑型和串珠型，有的ＳＰＲ阳性终末伸入第四脑室和延髓中央管及血管腔，说明ＳＰＲ阳性终末与脑脊液、血液之间存在某种信息交流。In order to study the distribution and morphological feature of SP receptor(SPR) positive structure in “medullary visceral zone(MVZ)” of rat, we observed the situation and morphological character of SPR systematically in MVZ of rat by immunohistochemical method. The results showed that SPR LI positive structure was concentrated in MVZ. The distribution was basically consistent with that of SP. Some of SPR LI positive neurons and fibers were densely stained, and some were sparsely stained. Some were large, and some small. The morphological variation also existed among them. SPR LI positive fibers could be divided into 3 kinds. They were wool shaped, smooth and varicose fibers. Some SPR terminal contact concisely with SPR positive neurons or dentrites. In present experiments, we also observed that the SPR LI fibers were extended into the epindymal layer of the fourth ventricle, the medular central canal, or the endodermis of the blood vessels. It was suggested that informational intercourse might exist between SPR positive terminals and cerebrospinal fluid or blood. It was verified that some of SPR LI neurons were SPR/TH double labelled neurons.

关 键 词：P物质受体 延髓内脏带 免疫组织化学 大鼠 

分 类 号：R338.2[医药卫生—人体生理学]