抗苗勒管激素与多囊卵巢综合征  

Study of Anti-müllerian Hormone and Polycystic Ovary Syndrome

作　　者：罗晓燕[1] 王蕊[2] 

机构地区：[1]四川大学华西第二医院妇产科,成都610041 [2]首都医科大学附属北京天坛医院

出　　处：《国际生殖健康／计划生育杂志》2010年第2期105-108,共4页Journal of International Reproductive Health/Family Planning

摘　　要：抗苗勒管激素(AMH)是唯一从初级卵泡到窦卵泡期由颗粒细胞产生的一种激素。AMH与卵泡发育、卵巢储备功能及围绝经期的预测均有很强的相关性,能有效评估辅助生殖技术的结果。因证实其能抑制卵巢始基卵泡的募集和卵泡刺激素(FSH)诱导的卵泡生长而逐渐引起重视。近年AMH与多囊卵巢综合征(PCOS)相关性日益得到重视,AMH与PCOS关系的研究有助于对PCOS发病机制的理解,并可能对PCOS诊断及治疗效果评估有一定意义。Anti-müllerian hormone（AMH）is produced in the ovary by the granulose cells（GC） surrounding preantral and small antral follicles stage.AMH can be used for assessing ovarian reserve,predicting peri-menopausal period,and involving folliculogenesis.It also can be used for evaluating the effect of ART.It has been suggested that AMH would inhibit the initiation of primordial follicle growth and FSH-induced follicle growth.In recent years,the correlation between AMH and PCOS became important.It maybe help to explain pathogenesy and assess diagnostic efficacy and therapeutic efficacy in PCOS patient.

关 键 词：抗苗勒管激素 多囊卵巢综合征 卵泡发育 胰岛素抵抗 二甲双胍 

分 类 号：R711.75[医药卫生—妇产科学]