新工艺护肝片的质量标准  

Quality Standard for Hugan Tablet of New Technology

作　　者：全红[1] 蔺莉莉[1] 张洪君[1] 鲁一[1] 董培良[1] 陈大中[1] 孙永慧[1] 张晓燕[1] 

机构地区：[1]黑龙江中医药大学中医药研究院,哈尔滨150040

出　　处：《中国药师》2010年第5期660-662,共3页China Pharmacist

基　　金：黑龙江省科技计划项目(No.GC06C32601);黑龙江省教育厅科技项目(No.1153136)

摘　　要：目的:制定新工艺护肝片的质量标准,验证新工艺的可行性。方法:对五味子、柴胡、猪胆粉进行薄层鉴别,用高效液相色谱法测定五味子醇甲的含量。结果:在选定的薄层色谱条件下,五味子、柴胡、猪胆粉的特征斑点清晰,五味子醇甲的线性范围为20.5～184.5μg·ml^(-1),r=0.999 9,平均回收率为99.2%,RSD0.57%,n=9。结论:护肝片的新工艺稳定,其质量标准专属性好。Objective： To formulate the quality standard for Hugan Tablet of new technology, and to verify the feasibility of new technology. Method： The Schisandra, Bupleurum and Pulvis fellis suis were identified by TLC, the content of Sehizandrol was determined by HPLC. Result： The spots in the TLC were clear, the linear range of schizandrol was 20.5-184.5 μg · ml^ - 1, r = 0.999 9, the average recovery was 99.2% with RSD O. 57% , n = 9. Conclusion： The technology of hugan tablets is stability the quality standard is specificity.

关 键 词：护肝片 新工艺 质量标准 

分 类 号：R285.5[医药卫生—中药学]