不规则抗体筛查对临床输血的意义  

The Clinical Significance of Irregular Antibodies Screening

作　　者：汪辉[1] 王京华[1] 苗美娟[1] 仝东霞[1] 刘菲[1] 韩碧清 陈曦[2] 

机构地区：[1]哈尔滨医科大学附属第二医院输血科,黑龙江哈尔滨150086 [2]哈尔滨医科大学附属第二医院血液科,黑龙江哈尔滨150086

出　　处：《现代生物医学进展》2010年第5期884-886,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨不规则抗体的筛查在临床输血中的意义。方法:对2009年5月至10月间本院6300例输血患者做不规则抗体筛查,抗体筛检阳性者做进一步鉴定,分析抗体特异性,总结各抗体出现频率。结果:半年来检测病例6300例,检测出不规则抗体阳性9例,阳性率0.14%,其中抗-D抗体2例,抗-DC抗体1例、抗-E抗体2例,抗-e抗体1例,抗-M抗体3例。还检测出自身抗体3例及高度冷凝集1例。结论:不规则抗体筛选应作为输血前检查之常规,对保障临床用血、预防溶血性输血反应具有极其重要的意义。Objective：To discussion the meaning of irregular antibodies screen in clinical transfusion. Methods： To screen irregular antibodies for 6300 transfusion patients in half a year of our hospital,and to further identify the positive samples.Then we analyzed their specification. Resttlts：9 samples were positive by detected and positive rate was 0.14 % in the 6300 cases.There were anti-D antibody 2 cases,anti-DC antibody 1 case ,anti-E antibody 2 cases ,anti-e antibody 1 case and anti-M antibody 3 cases. 3 cases anto-antibodies and 1 case cold agglutination had been detected. Conclusion：Screening irregular antibodies should be the routine pre- transfusion examination. It has important significance in ensuring clinical blood and preventing hemolytic transfu- sion reaction.

关 键 词：不规则抗体 抗体筛查 溶血性输血反应 

分 类 号：R457.1[医药卫生—治疗学]