右心室间隔部起搏对血流动力学的影响  

Effects of pacing in right ventricle septum on hemodynamics.

在线阅读下载全文

作  者:郭俊芳[1] 鲍中华[1] 张国辉[1] 真亚[1] 李卫东[1] 汪建飞[1] 孙琴芳[1] 张凤琴[1] 

机构地区:[1]江苏省镇江市第一人民医院心内科江苏大学附属人民医院心内科,212002

出  处:《中国综合临床》2010年第5期476-479,共4页Clinical Medicine of China

摘  要:目的评价在房室顺序起搏治疗中,右心室间隔部起搏对血流动力学的影响。方法20例植入双腔起搏器的患者,高度房室传导阻滞6例,完全性房室传导阻滞14例,按照心室电极的位置分为右心室心尖部起搏(RVA)组和右心室间隔部起搏(RVS)组。对2组患者术前、术后3个月随访时的QRS波形态和宽度、左心室射血分数(LVEF)、心室间机械运动延迟(IVMD)和血脑钠肽(BNP)水平进行比较。结果与术前相比,RVA组起搏心电图QRS时限增宽[(187.00±15.67)ms与(94.00±9.17)ms,t=15.98,P〈0.05],LVEF下降[(53.70±1.34)%与(58.60±1.65)%,t=7.30,P〈0.05],IVMD延长[(43.20±6.79)ms与(15.00±4.08)ms,t=7.75,P〈0.05],BNP升高[(89.70±8.30)ng/L与(40.00±4.73)ng/L,t=16.44,P〈0.05],而RVS组无明显变化(P均〉0.05);术后和RVA组相比,RVS组QRS时限缩短[(119.00±7.38)ms与(187.00±15.67)ms,t=12.42,P〈0.05],LVEF增加[(57.00±2.00)%与(53.70±1.34)%,t=4.09,P〈0.05],而IVMD缩短[(19.00±4.59)ms与(43.20±6.79)ms,t=7.94,P〈0.05],BNP降低[(44.20±9.18)ng/L与(89.70±8.30)ng/L,t=11.62,P〈0.05]。结论和传统的RVA起搏相比,RVS起搏尽可能地维持了双心室的正常激动顺序和双心室的同步性,对血流动力学的影响较小,RVS起搏比RVA起搏更接近生理性起搏。Objective To evaluate the effects of pacing in right ventricular septum (RVS) on hemodynamics among atrioventricular sequential dual chamber pacing. Methods Twenty patients with high grade or complete atrioventricnlar block received permanent dual chamber pacemaker ( DDD ) , were randomized into right ventricular septum pacing group (RVS)and right ventricular apex pacing group (RVA)according to the ventricular leads position. The QRS duration of the ECG, the left ventricular ejection (LVEF) , the interventricular mechanical delay ( IVMD ) and the plasma levels of brain natriuretic peptide ( BNP ) were compared before and after operations. Results Compared with the preoperation, the mean QRS duration( ( 187.00 ± 15.67 )ms and (94. 00 ± 9. 17 ) ms) , the IVMD ( (43.20 ± 6. 79 ) ms and ( 15.00 ± 4. 08 ) ms) , the level of BNP ( ( 89.70 ± 8.30 ) ng/L and (40. 00 ±4. 73) ng/L) inereased(P 〈0. 05) and LVEF decreased significantly ( (53.70 ±1.34)% and (58. 60 ± 1.65 ) % ,P 〈 0.05 ) in RVA group, but didn't change in RVS group ( P 〉 0. 05 ). After three months following up, the mean QRS duration and the IVMD in RVS group( ( 119. 00 ± 7.38 ) ms, ( 19. 00 ± 4. 59 ) ms) were shorter than that of RVA group ( ( 187.00 ± 15.67 ) ms, (43.20 ±6. 79 ) ms ) ( P 〈 0. 05 ), the LVEF was higher and the plasma level of BNP was lower than that of RVA group ( ( 57.00 ± 2. 00) % and ( 53.70 ±1.34 ) %, (44. 20 ± 9. 18 ) ng/L and ( 89. 70 ± 8.30) ng/L,P 〈 0. 05 ). Conclusions The RVS pacing could keep the normal ventrieular activation sequence and biventricular contraction synehrony farthest without side effects on hemodynamies in comparison with the RVA pacing. The RVS pacing is more approaching physiological rhythm than the RVA pacing.

关 键 词:心脏起搏 右心室间隔部 右心室心尖部 血流动力学 

分 类 号:R541.7[医药卫生—心血管疾病]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象