萸连止泻丸提取工艺研究  

Optimum Extraction Process of Yulian Zhixie Pills

作　　者：王启斌[1,2] 陈黎[2] 李炯[2] 郝新才[2] 何文[1] 

机构地区：[1]武汉大学药学院,430070 [2]郧阳医学院附属太和医院药学部,湖北十堰442000

出　　处：《医药导报》2010年第5期644-646,共3页Herald of Medicine

摘　　要：目的优选萸连止泻丸最佳提取工艺。方法以小檗碱含量与干膏得率为评价指标,采用高效液相色谱法测定含量,采用正交实验考察加水量、煎煮时间、煎煮次数对提取效果的影响。结果最佳提取工艺为10倍量水,煎煮3次,每次1.5 h。结论该提取工艺设计合理,结果可靠,可为萸连止泻丸提取工艺提供理论基础。Objective To optimize the conditions of extraction tot yulian zhixie pills. Methods HPLC was used to analyze the content of yulian zhixie pills, and the orthogonal experimental design was introduced to optimize the conditions of the extraction technology. The amount of water,time and times of dccoeting on extraction were studied by the orthogonal design. Results The conditions of the water extraction technology for isolating the constituents from yulian zhixie pills were using 10-fold solvent, taking 1.5 hour and extracting for 3 times. Conclusion The process is reasonable and reliable, which provides us a theoretical base for study yulian zhixie pills.

关 键 词：萸连止泻丸 提取工艺 正交实验 

分 类 号：R286[医药卫生—中药学] TQ460.1[医药卫生—中医学]