猪脱碘酶3基因定位及对生产性状的潜在影响  

Mapping of Porcine DIO3 Gene and Analysis of Its Potential Influence on Production Traits

作　　者：蒋晓玲[1] 赵晓枫[1] 郭晓令[1] 徐宁迎[1] 

机构地区：[1]浙江大学动物科学学院,杭州310029

出　　处：《畜牧兽医学报》2010年第4期383-386,共4页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：浙江省科技厅重大项目(2005C12005-2);浙江省重大科技攻关项目(2006C004-(2))

摘　　要：为确定猪脱碘酶3(DIO3)基因能否作为某些生产性状的候选基因,本研究设计猪DIO3基因特异引物,采用辐射杂种细胞系,将其定位在猪7号染色体微卫星SW764附近。通过比较猪QTL数据库,发现该座位存在7个分别影响猪肌纤维直径、内脂率、胴体长、胴体质量、皮质醇水平调控的QTL,结果表明DIO3基因可作为猪肉质性状、胴体性状和应激相关性状的候选基因。To investigate if porcine DIO3 gene could be used as a candidate gene influencing some production traits of porcine,porcine DIO3 gene specific primers were designed and used in the radiation hybrid mapping.The RH mapping result showed that this gene was near to the microsatellite SW764 on chromosome 7.Seven QTLs for muscular fiber diameter,internal fat percentage,carcass length,carcass weight,and cortisol level,respectively,were found at this locus by searching pig QTL database.The results suggest that DIO3 could be a candidate gene for porcine meat quality traits,carcass traits and stress response.

关 键 词：猪 脱碘酶3基因 RH定位 候选基因 

分 类 号：S828[农业科学—畜牧学] S813.1[农业科学—畜牧兽医]