新生儿缺氧缺血性脑病时血生化的改变与临床意义  

A Series of Change in the Serum Biochemistry and Trestment on Neonatal HIE.

作　　者：张艳缇[1] 王俊怡[1] 李月梅[1] 李根山[1] 谭国军[1] 刘秋月[1] 刘名才[1] 尹济群[1] 张琳[2] 黎珉 靳桂芝 翟春雪 王宝全 周琰[4] 

机构地区：[1]河北医科大学第二医院儿科,石家庄050000 [2]河北医科大学第三医院 [3]石家庄市新华医院 [4]石家庄铁路中心医院检验科

出　　处：《中华儿童保健杂志》1998年第1期22-23,共2页

摘　　要：目的 为评价及分析新生儿HIE的系列生长变化.方法 对43例中重度新生儿HIE急性期,恢复期血清多项生化指标进行了测定,并与正常新生儿作对照比较.结果 中重度新生儿HIE急性期存在血乳酸和血氨增高;血清钙离子和过氧化物歧化酶(SOD)降低;心肌酶增高;尿素氮增高;血钠及二氧化碳结合力降低.结论 新生儿HIE时伴有机体多脏器的损伤,应引起临床足够重视.Objective To evaluate and analysis the series of change in serum biochemistry on neonatal HIE classified as moderate of severe. Methods 43 cases of neonatal HIE (experimental group included actue stage 32 cases, convalesence 11 cases) and normal control group 15 cases were studied prospectively . Results Serum lactic acid, ammonia, BUN and activity of myocardial enzyme was increased obviously and Ca2+ ,SOD,Na2+ and CO2CP was decreased in the acute stage of morderate or severe neonatal HIE. Conclusion The acute stage HIE have dysfunction of multiple organs,It's important to mornitor the biochemical markers in time on acute stage of morderate or severe neonatal HIE for treatment and improving prognosis.

关 键 词：新生儿 临床意义 缺氧缺血性脑病 生物化学 血液 

分 类 号：R722.12[医药卫生—儿科]