广东省社区美沙酮维持治疗剂量使用现状及其评价  

DOSAGE USING IN COMMUNITY METHADONE MAINTENANCE TREATMENT AT CLINICS IN GUANGDONG AND ITS EVALUATION

作　　者：陈君[1] 陈雯[1] 凌莉[1] 夏英华[1] 何群[2] 陈昂[1] 韩璐[1] 

机构地区：[1]中山大学公共卫生学院医学统计与流行病学系,广州510080 [2]广东省疾病预防控制中心

出　　处：《现代预防医学》2010年第9期1687-1689,共3页Modern Preventive Medicine

摘　　要：[目的]研究目前广东省社区美沙酮维持治疗的剂量使用现状,并对其进行评价。[方法]使用国家美沙酮维持治疗管理软件,收集全省45个门诊维持治疗剂量数据并整理,以门诊为单位,年份、地区为分层因素,对各门诊的剂量使用情况进行分析,并与国家标准进行比较。[结果]2006～2008年,首次平均剂量为43.54mg/d,维持期平均剂量为46.11mg/d。50%的门诊的首次剂量和90%的门诊的维持期平均剂量低于国家建议标准。维持期每次剂量调整幅度14.18mg/d。[结论]目前广东省社区美沙酮维持治疗的首次给药剂量较低,维持剂量给予不足,维持期剂量调整幅度较大,应提高各门诊的维持剂量、减少剂量调整幅度,以提高美沙酮的维持治疗效果。[Objective] To conduct a study and evaluation on the dosage using status in community-based methadone maintenance treatment （MMT） clinics in Guangdong province. [Methods] The data of 45 MMT clinics were collected through the national MMT management system. Stratified the clinics by year and districts, analyzed the dosage using in each clinics and compared with national standard. [Results] From 2006 to 2008, the average initial dosage was 43.54 mg / d, average maintaining dosage was 46.11 mg / d. The initial dosage of 50% clinics and maintaining dosage of 90% clinics were lower than national standard. The adjusting degree was 14.18 mg / d per time. [Conclusion] The initial dosage of maintaining dosage is insufficient and the adjusting degree is large. To improve the effectiveness of MMT, maintaining dosage should be risen and adjusting dosage should be reduced.

关 键 词：美沙酮维持治疗 维持剂量 评价 

分 类 号：R195[医药卫生—卫生统计学]