颈动脉与冠状动脉粥样斑块的相关性研究  

STUDY ON CORRELATION OF CAROTID ARTERY ATHEROMATOUS PLAQUE AND CORONARY ARTERY ATHEROMATOUS PLAQUE

作　　者：叶红梅[1] 

机构地区：[1]绵阳市第三人民医院,绵阳62100

出　　处：《现代预防医学》2010年第9期1768-1769,共2页Modern Preventive Medicine

摘　　要：[目的]探索颈动脉粥样斑块与冠状动脉粥样斑块的相关性。[方法]选取2008.01～2009.05入住某院心内科的患者89例作为研究对象,依据冠状动脉造影将其分为研究组及对照组。用超声检测两组患者颈动脉粥样斑块的分布情况,将造影结果与超声检测结果进行统计处理。[结果]研究组45例检出斑块,对照组中33例未检出斑块,两组病例颈动脉内中膜厚度差异有统计学意义(t=2.6959,P=0.0084);颈动脉狭窄程度与冠状动脉粥样斑块相关(χ2=50.7788,P=0.0000,Pearson列联系数=0.6027);颈动脉粥样斑块发生的部位数与冠状动脉粥样斑块发生的血管支数有关(χ2=69.5209,P=0.0000,Pearson列联系数=0.6622)。颈动脉内中膜厚度增加的程度与冠脉脉粥样斑块的相关性不确定(rs=0.6,P﹥0.05)。通过颈动脉粥样斑块的情况了解冠脉粥样斑块的情况,Sen=88.2353%,Spe=86.8421%,Acc=87.6404,YI=0.7508。[结论]颈动脉粥样斑块与冠状动脉粥样斑块是相关的,通过超声检测颈动脉粥样斑块,间接了解心肌冠状动脉粥样斑块情况是可行的,可指导冠心病患者的治疗、效果判断、随访观察。[Objective] To explore the correlation between carotid artery atheromatous plaque and coronary artery atheromatous plaque. [Methods] As the research subjects, selected 89 cases of cardiology in our hospital from Jan.2008 to May, 2009. They were divided into study group and control group based on coronary angiography. And then detected the carotid artery of patients in two groups in order to know the information about atheromatous plaque with ultrasonic scan, and treated the data on ultrasound imaging and coronary angiography with statistical software. [Results] 45 patients were detected out the atheromatous plaque in study group, 33 cases were not detected out the atheromatous plaque in control group, significant difference （t = 2.6959, P = 0.0084） of intima-media thickness （IMT） were founded in the two groups; the degree of carotid artery stenosis was related to coronary artery atheromatous plaque （χ^2 = 50.778 8, P = 0.000 0, Pearson coefficient of contingency= 0.602 7）; while the number of the site of carotid artery atheromatous plaque was related to the count of the coronary artery with atherosclerotic plaque （χ^2 = 69.520 9, P = 0.000 0, Pearson coefficient of contingency = 0.6622）. The correlation between the degree of IMT increased in carotid artery and coronary artery atheromatous plaque was uncertain （rs = 0.6, P﹥0.05）. Furthermore, we could gain the information of the coronary artery atheromatous plaque through the carotid artery plaques, Sen = 88.2353%, Spe = 86.8421%, Acc = 87.640 4, YI = 0.750 8. [Conclusion] Carotid artery atheromatous plaque and coronary artery atheromatous plaque are relevant. It is feasible to understand the coronary plaque through the carotid artery plaque. Futhermore, it is useful to guide our treatment, judgment, follow-up for patients with coronary heart disease.

关 键 词：粥样斑块 颈动脉 冠状动脉 相关性 超声检测 

分 类 号：R543[医药卫生—心血管疾病]