一起新型甲型H1N1流感疫情的临床和实验室特点  

Clinical and laboratory characteristics of a new influenza A （ H1N1 ） epidemic

作　　者：冯艳青[1] 郭桐生[1] 刘立明[1] 李永利[1] 李波[1] 刘志国[1] 孙志强[1] 赵敏[2] 毛远丽[1] 李伯安[1] 

机构地区：[1]中国人民解放军第三0二医院临检中心,北京100039 [2]中国人民解放军第三0二医院感染一科,北京100039

出　　处：《中华实验和临床病毒学杂志》2010年第2期134-135,共2页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的分析一起新型甲型H1N1流感疫情患者的临床和实验室特点。方法某部集体发病患者35例，均由核酸检测方法确诊；回顾调查患者的密切接触史、实验室检测结果、治疗和预后等。结果本次疫情收治的35人，密切接触平均1．7d出现临床症状，首发症状为发热占97．1％（34／35），咽痛65．7％（23／35），咳嗽51．4％（16／35），肌肉酸痛31．4％（11／35），头痛28．6％（10／35）。病毒核酸检测阴性的平均天数为4．5d，奥司他韦治疗，5d标准疗程，所有患者7d后痊愈出院。结论本次疫情为比较典型的新型甲型H1N1流感。Objective To analysis the clinical and laboratory characteristics of Patients infected with new influenza A （ H1N1 ） virus. Methods All cases with new influenza A （ H1N1 ） confirmed on polymerase chain reaction assay on throat swabs. There were included in a prospective evaluation of clinical characteristics, laboratory results, treatment and overcome of new influenza A （H1N1）. Results There were 35 patients in the epidemic. Clinical illness developed within a mean of 1.7 days. Fever occurred in 97.1% , sore throat 65.7% cough 51.4% , headache 28.6% , and myalgia 31.4%. All patients were treated with osehamivir lasted 5 days. The mean duration of viral shedding was 4.5 days. All were cured and left hospital after day 7. Conclusion It was infected by new influenza A （H1N1） typically in this epidemic.

关 键 词：流感 流感病毒A型 疾病暴发流行 

分 类 号：R511.7[医药卫生—内科学]