老年男性2型糖尿病患者下肢血管病变与骨质疏松的关系  

Relationship Between Vascular Lesions in the Lower Extremities and Osteoporosis in Elderly Male People with Type 2 Diabetic Mellitus

作　　者：杨虹[1] 卢学勉[1] 林爱菊[1] 黄贤恩[1] 曾伟伟[1] 

机构地区：[1]温州医学院附属第三医院内分泌科,浙江省瑞安市325200

出　　处：《中国动脉硬化杂志》2010年第1期75-77,共3页Chinese Journal of Arteriosclerosis

摘　　要：目的探讨老年男性2型糖尿病患者下肢血管病变与骨质疏松的关系。方法老年男性2型糖尿病患者148例,采用双能X线吸收法测定腰椎骨和股骨区的骨密度,同时用超声探测双下肢动脉内膜中膜厚度及粥样斑块等情况。结果无血管病变组33例,轻中度血管病变组65例,重度血管病变组50例,三组间骨密度值依次降低(P<0.05或0.01);多元Logistic回归分析显示,仅年龄、体质指数、下肢血管病变积分为决定骨质疏松的独立危险因素(OR值分别为1.50、0.52及1.87)。结论老年男性2型糖尿病下肢血管病变患者骨密度减低,骨质疏松风险增加。Aim To observe the relationship between vascular lesions in the lower extremities and osteoporosis in elderly male people with type 2 diabetic mellitus.Methods 148 elderly male patients with type 2 diabetic mellitus were enrolled.All patients underwent ultrasonography for both sides of artery of lower extremity.They also underwent dual-energy X-ray absorptiometry（DXA）examination to determine the bone mineral density（BMD）of the vertebra and the femoral head.According to a lower extremity vascular disease severity score,the patients were divided into control group,mild-moderate group and severe group.Results BMD was significantly different among three groups（P〈0.05 or 0.01）,the more severe lower extremity vascular disease,the lower the bone mineral density was.Only age,body mass index（BMI）and lower extremity vascular disease severity score correlated to osteoporosis by multiple regression analysis.Conclusion Elderly male people with type 2 diabetic mellitus and vascular lesions in the lower extremities tend to have lower BMD,they may have increased prevalence of osteoporosis.

关 键 词：骨质疏松 2型糖尿病 下肢血管病变 骨密度 

分 类 号：R5[医药卫生—内科学]