系统性血管炎合并肠梗阻12例临床分析  

Clincal Analysis of 12 Cases of Systemic Vasculitis with Intestinal Obstruction

作　　者：班宗文[1] 赵威[1] 鲁重美[1] 赵岩[2] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院消化内科,北京100073 [2]中国医学科学院北京协和医学院北京协和医院风湿免疫科,北京100073

出　　处：《临床消化病杂志》2010年第2期99-101,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：目的总结分析系统性血管炎合并肠梗阻病例的临床特点,以提高对该疾病的认识。方法回顾总结12例系统性血管炎合并肠梗阻病例的临床资料,分析其临床特点。结果12例患者中,白塞病8例,变应性肉芽肿血管炎1例,巨细胞动脉炎1例,未分类2例,男性8例,女性4例,中位年龄44岁。9例患者在病程中并发肠梗阻,多为慢性不全肠梗阻。其中3例以肠梗阻表现为首发症状,均表现为急性完全性肠梗阻。所有病例血沉均升高,自身抗体中抗核抗体阳性1例,抗中性粒细胞胞浆抗体-核周型(pANCA)阳性1例。结论肠梗阻可以为系统性血管炎的首发症状或并发表现,应重视该疾病,避免不必要的外科手术。Objective To improve the understanding of the clinical characteristics of systemic vasculitis with intestinal obstruction. Methods The clinical features of 12 patients of systemic vasculitis with intestinal obstruction were reviewed. Results Among 12 patients ,8 cases were Behcet disease ,followed by 1 case of churg-strauss syndrome, 1 cases of giant cell arteritis, and 2 cases of unclassified;8 cases were male and 4 cases were female with the median age of 44 years. Acute and complete intestinal obstruction was the first symptom in 3 cases, and in another 9 cases intestinal obstruction was a complication. ESR was elevated in all case with antinuclear antibody positive only in I case and with pANCA positive in I cases. Conclusion Intestinal obstruction can be the initial symptom or the complicated sign in the systemic vasculitits, clinical doctors should be alert to this kind of diseases.

关 键 词：系统性血管炎 肠梗阻 白塞病 抗中性粒细胞胞浆抗体 

分 类 号：R597[医药卫生—内科学] R656.7[医药卫生—临床医学]