计算骨丧失量经椎弓根打压植骨治疗胸腰椎压缩性骨折的生物力学研究  

Transpedicular impacted grafting after bone loss calculation in the treatment of thoracolumbar compression fracture:a biomechanical study

作　　者：樊道斌 朱敏[1] 甘业春 叶春万 王欣[1] 谢昌宏 吴信忱 

机构地区：[1]安徽省巢湖市骨科医院脊柱外科,巢湖市238000

出　　处：《中国矫形外科杂志》2010年第8期654-658,共5页Orthopedic Journal of China

摘　　要：[目的]探讨用计算骨丧失量的方法经椎弓根打压植骨(transpedicular impacted grafting,TPIG)治疗胸腰椎压缩性骨折的生物力学性能。[方法]将6具成人新鲜尸体胸腰椎标本,模拟正常组、压缩性骨折损伤组、单纯计算骨丧失量TPIG和单纯经椎弓根植骨组(transpedicular grafting,TPG)、计算骨丧失量TPIG+椎弓根固定和TPG+椎弓根固定组,行生物力学实验应力分析,比较各组的椎体和椎间盘的强度、刚度和稳定性以及扭转生物力学性能。[结果](1)计算骨丧失量TPIG+椎弓根固定组的椎体和椎间盘的强度、刚度和稳定性高于TPG+椎弓根固定组,具有显著性差异(P<0.05);(2)单纯计算骨丧失量TPIG组的强度和刚度高于单纯TPG组,并具有显著性差异(P<0.05);(3)从扭转生物力学试验中也同样得到了相似的结论。[结论]计算骨丧失量TPIG+椎弓根固定治疗胸腰椎压缩性骨折具有优越的生物力学性能,适合于临床应用。[ Objective ] To investigate the biomechanical properties of transpedicular impacted grafting （ TPIG ） after bone loss calculation in the treatment of thoracolumbar compression fracture. [ Method ] Six fresh human thoracolumbar spine （ T12 - L2 ） specimens were tested as 6 models ： normal control （ group A ）, compression fracture （ group B）, TPIG after bone loss calculation （group C）,transpedicular grafting （TPG） （group D） ,TPIG after bone loss calculation ＋ pedicle fixation （group E）,TPG ＋ pedicle fixation （group F）. Biomechanical analysis was carried out to test the intensity, stiffness, stability and torsion properties between different groups. [ Result ] The intensity, stiffness and stability of vertebral body and intervertebral disc in group E were higher than those in group F,with significant difference （ P 〈 0.05 ）. The intensity and stiffness in group C were higher than those in group D, with significant difference （ P 〈 0.05 ）. Similar results were fuund in biomechanical torsion test, with significant differenee （P 〈0.05）. [ Conclusion] Transpedicular impacted grafting after bone loss calculation combined with pediele fixation has better biomechanieal properties,it is suitable for clinical application.

关 键 词：胸腰椎压缩性骨折 计算骨丧失量 经椎弓根打压植骨 内固定 生物力学 

分 类 号：R687.3[医药卫生—骨科学] R318.01[医药卫生—外科学]