银杏叶提取物预防继发性脊髓损伤机制研究  

Ginkgo Biloba Extract to Prevent Secondary Spinal Cord Injury Mechanisms Research Progress

作　　者：姚冬梅[1] 杨拯[1] 黄叶[1] 李文洁[1] 熊六波[1] 陈兵[1] 张晓[1] 

机构地区：[1]成都医学院,四川成都610083

出　　处：《辽宁中医药大学学报》2010年第5期248-251,共4页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：成都医学院实验室开放项目(KF200936)

摘　　要：随着银杏叶提取物(Ginkgo biloba extract,EGb)药理作用机制的阐明,发现银杏叶提取物有多种功能,如抗氧化、清除自由基、抑制脂质过氧化、抗血小板活化因子、扩张血管、减轻炎症反应、抗细胞凋亡,对继发性脊髓损伤有一定的预防作用。根据EGb能保护血管内皮、清除自由基、抑制炎症反应、抗细胞凋亡及抑制谷氨酸毒性等作用,对预防继发性脊髓损伤作如下综述。As Ginkgo biloba extract（EGb） clarify the mechanism of pharmacological action and found that EGb has a wide range of functions,such as anti-oxidation,scavenging free radicals,inhibit lipid peroxidation,anti-platelet-activating factor,the expansion of blood vessels,to reduce the inflammatory reaction,anti-apoptosis,secondary spinal cord injury to have a certain preventive effect.The article,EGb on the prevention of secondary spinal cord injury in vascular endothelial protection,removal of free radicals and inhibit inflammatory response,anti-apoptosis and inhibition of glutamate toxicity is summarized below.

关 键 词：继发性脊髓损伤 银杏叶提取物 预防 

分 类 号：R827.11[医药卫生—临床医学]