银杏根皮中萜内酯提取工艺研究  

Extraction of ginkgolides from Ginkgo biloba

作　　者：何珺[1] 杨硕[1] 杨佳年[1] 卿晓红[1] 

机构地区：[1]贵州省生化工程中心,贵州贵阳550025

出　　处：《中国中药杂志》2010年第9期1127-1129,共3页China Journal of Chinese Materia Medica

基　　金：贵州省科技厅2001年省基金项目(20013096);贵州省科技厅2008年省重大专项项目(20086020)

摘　　要：目的:探索出以乙醇-水为浸提溶剂的银杏根皮中萜内酯的提取工艺,确定最佳提取参数。方法:通过对银杏根皮提取参数中浸提温度、浸提时间、料液比、浸提醇浓度、浸提酸度进行单因素梯度试验,采用HPLC法检测含量,确定银杏根皮中萜内酯浸提最佳参数。结果:银杏根皮中萜内酯最佳浸提条件:浸提时间2h;料液比1∶15;浸提温度50℃;浸提液pH3;30%乙醇。结论:以乙醇-水为溶剂从银杏根皮中提取萜内酯的方法具可行性和生产应用价值。Objective： To establish the technology for extraction of ginkgolides from Ginkgo Biloba with alcohol-water. Method： The parameters such as alcohol concentration, pH of extracting solution, ratio of dosage liquor, temperature and time, the extraction of ginkgolides from G. biloba was investigated, and its parameters were optimized. Result： The optimized parameters were alcohol concentration 30%, extracting temperature 50 ℃, extracting time 2 h, pH 5 solid-liquid ratio 1： 15. Conclusion： This method has the merits of low cost and simple operation.

关 键 词：银杏根皮 萜内酯 提取 

分 类 号：R284.1[医药卫生—中药学]