天津市2004-2008年麻疹高发原因分析  

Analysis of measles eipidemic in Tianjin,2004-2008

作　　者：朱向军[1] 张之伦[1] 丁亚兴[1] 骆晓艳[1] 张颖[1] 田宏[1] 

机构地区：[1]天津市疾病预防控制中心免疫规划科,300011

出　　处：《中国公共卫生》2010年第5期626-627,共2页Chinese Journal of Public Health

摘　　要：目的探讨天津市2004-2008年麻疹发病升高的原因,为防制麻疹提供科学依据。方法利用麻诊监测及调查资料对天津市近年麻疹流行特征、人群抗体、院内感染状况等进行分析。结果近5年来,天津市麻疹发病率从2004年的0.67/10万增至2008的年21.97/10万,发病年龄构成以婴儿和成人为主,占60%～,其中<1岁组麻疹发病率最高;1～6岁麻疹患者流动人口约占50%;2005-2008年,28起麻疹暴发疫情中,13起发生在企业。病例对照研究显示,医院内感染的OR=41.0(95%CI=17.2～97.8),2007年健康人群麻疹抗体阳性率为91.78%,保护率为75%。结论天津市近年来麻疹增高原因主要与接种率低、易感人群积累、继发性免疫失败、医院内感染、流动人口增加有关。Objective To explore the reason for high measles incidence rate in Tianjing city from 2004 to 2008 for measles control.Methods The antibody level,nosocomial infection of mesales were analyzed with the data of measles surveillance and investigation.Results The measles incidence rate increased from 0.67/105 in 2004 to 21.97/105 in 2008 and the incedence rate of 1 year age group was the highest.More than 50% of all cases in 1-6 year age group occured in floating population.There were 28 mesales outbreaks in 2005-2008,and 13 outbreaks in companies.Nosocomial infection was one of risk factors of measles（odds ratio=41.0,95% confidence interval=17.2-97.8）.In 2007,the antibodies positive rate of measles was 91.78% in healthy people and the protective rate was 75%.Conclusion The major reasons for measles epidemic in Tianjin were low immunization coverate of measles vaccine,accumulation of unvaccinated people,secondary immunization failure,nosocomial infection,and the increase of floating people.

关 键 词：麻疹 流行 医院内感染 麻疹监测 

分 类 号：R511.1[医药卫生—内科学]