溶菌酶及其晚期糖基化终产物(AGEs)与糖尿病并发症的研究  

A Research on Lysozyme,Advanced Glycation End-products (AGEs) and Diabetic Complications

作　　者：王利娟[1] 刘誉[2] 

机构地区：[1]华南农业大学生命科学学院,广东广州510642 [2]暨南大学医学院生物化学实验室,广东广州510640

出　　处：《临床医学工程》2010年第5期156-158,共3页Clinical Medicine & Engineering

摘　　要：溶菌酶又称胞壁质酶或N-乙酰胞质聚糖水解酶,其广泛分布于自然界各种生物体内,是一种无毒、无害、安全性很高的蛋白酶,被广泛应用于食品、饲料、医药等行业。本文重点介绍其在医药方面的应用,主要介绍溶菌酶如何通过去除晚期糖基化终产物来达到治疗糖尿病并发症效果的研究进展。Lysozyme, also known as muramidase or N-acetylmuramide glycanohydrlase, is a non-poisonous and innocuous protease, which is widely distributed in all living organisms in nature, and is widely used in food, forage, medicine and other industries. This article focuses on the application of lysozyme in medicine, which mainly describes the research advances on lysozyme by way of removal of advanced glycation end products to achieve the effect of treatment of diabetic complications.

关 键 词：溶菌酶 药理作用 晚期糖基化终产物(AGEs) 糖尿病并发症 

分 类 号：R687.42[医药卫生—骨科学]