迟钝爱德华菌感染大鲵的研究  

Study on Infection in Andrias davidianus Caused by Edwardsiella tarda

作　　者：敖弟书[1] 吴中明[1] 王玉[1] 张德刚[1] 李晓琴[1] 

机构地区：[1]遵义医学院微生物学教研室,贵州遵义563003

出　　处：《四川动物》2010年第3期411-414,共4页Sichuan Journal of Zoology

基　　金：基金项目:黔科合NY字[2006]3045

摘　　要：目的研究迟钝爱德华菌对大鲵的致病性,为防治提供实验依据。方法用不同浓度(102～108cfu/ml)迟钝爱德华菌,通过不同的感染途径(喂养的水环境、灌喂及注射)感染大鲵,观察病原菌的致病条件及大鲵各组织器官的细菌分布(皮肤、消化道、肝、脾、血液)和病理变化及敏感抗生素的治疗作用。结果喂养的水环境不能感染,大量灌喂(106～108cfu/ml)出现轻微感染症状,注射感染(104～107cfu/ml)出现明显感染症状,且部分死亡。感染后细菌分布于皮下、血液、肝、脾、胃等器官。用敏感抗生素处理后病鲵好转。结论迟钝爱德华菌对大鲵可能是一种机会致病菌,病菌感染大鲵需要合适的入侵途径和数量,感染后用敏感抗生素进行治疗有较好效果。To study the pathogenicity of Edwardsiella tarda to Andrias davidianus and how to prevent and control it. Methods Different concentrations of E. tarda （102～108cfu/ml） were used to infect A. davidianus through several distinct routes including living in bacterium-contained environments,feeding in bacterium-contained water,and injection of bacterium-contained water. The pathogenic conditions of this bacterium,its distribution in organs （such as skin,alimentary canal,liver,spleen,and blood）,pathological changes of infected A. davidianus,and therapeutic effect of the antibiotic on the infection were reconded. Results Living in bacterium-contained environments could not cause infection,and feeding （106～108cfu/ml） could cause mild infection,whereas injection （104～107cfu/ml） could cause remarkable symptom of infection,and even death. The bacteria appeared in skin,blood,liver,spleen,and stomach of infected individuals. Antibiotics could relieve symptoms of infected A. davidianus. Conclusion The results indicated that tolerant infection would appear in A. davidianus,and infection would be cured by sensitive antibiotic.

关 键 词：大鲵 迟钝爱德华菌 感染 

分 类 号：S947.3[农业科学—水产养殖]