多组分天然药物吸附等温线测定的研究  

Study of the Determination on Natrual Drug Adsorption Isotherm

作　　者：周丹[1] 张春才 

机构地区：[1]辽宁科技大学理学院,辽宁鞍山114044 [2]中冶焦耐工程技术有限公司,辽宁鞍山114001

出　　处：《沈阳理工大学学报》2010年第1期83-86,共4页Journal of Shenyang Ligong University

基　　金：科技型中小企业技术创新基金项目(03C26212100852)

摘　　要：吸附等温线可以表示色谱中被分离组分在固定相和流动相之间浓度平衡的关系,对色谱过程模拟和制备色谱工艺设计有很重要的作用.文中利用人工补偿逆方法测定表没食子儿茶素没食子酸酯(EGCG)的吸附等温线,并与迎头色谱法得到的结果进行比较.结果表明,通过人工补偿逆方法用二组分近似拟合确定多组分的吸附等温线是可行的,符合多组分吸附竞争特性,能够合理地反映杂质对吸附特性的影响.Adsorption isotherm presents the equilibrium concentrations of the components be- tween the stationary phase and the mobile phase, and is of importance to the design and simu- lation of the separation process in chromatographic column. The main work is to determine the adsorption isotherm of EGCG by inverse method of artificial compensation and to compare with the results obtained by frontal analysis method. The results show that the two-component approximation, the isotherms multi-component are fitted by inverse method with artificial compensation, it can also present the charater of competitive adsorption and the influence of impurities in the mixture on the adsorption charater.

关 键 词：非线性色谱 数学模型 EGCG 人工补偿逆方法 迎头色谱法 

分 类 号：O657.7[理学—分析化学] TQ018[理学—化学]