大剂量甲氨蝶呤治疗恶性淋巴瘤患者的护理  

The nursing of malignant lymphoma patients who used high dose MTX

作　　者：吴惠琼[1] 柯娜[1] 廖瑞梅[1] 

机构地区：[1]江门市中心医院肿瘤二区,529400

出　　处：《国际医药卫生导报》2010年第10期1238-1241,共4页International Medicine and Health Guidance News

摘　　要：目的总结采用大剂量甲氨蝶呤化疗的恶性淋巴瘤患者的护理对策。方法对36例恶性淋巴瘤患者采用大剂量甲氨蝶呤方案化疗，全程观察治疗过程所出现的护理问题，记录并总结其要点。结果HD-MTX化疗后恶心、呕吐发生率最高，达到52．8％，神经毒性最少，为5．6％，不良反应前四位依次为恶心、呕吐，ALT升高，血小板减少和口腔粘膜炎。结论护士需要熟悉药物的特性和毒性反应，并及早预防、及时处理和加强毒性反应护理，这样才能保证化疗的顺利进行。Objective To evaluate the use of high-dose methotrexate chemotherapy for patients with malignant lymphoma Nursing. Method 36 cases of malignant lymphoma treated with highdose methotrexate chemotherapy, observed throughout the course of treatment of care problems arising from, record and summarize its key points. Results HD - MTX chemotherapy nausea and vomiting, the incidence of the highest, reaching 52.8%, neurotoxicity least 5.6%, followed by adverse reactions before the 4 nausea, vomiting, ALT increased, thrombocytopenia, oral mucositis. Conclusions Nurses need to be familiar properties and toxicity of drugs, and early prevention and timely treatment and strengthen the toxicity of care, so as to ensure the smooth progress of chemotherapy.

关 键 词：大剂量甲氨蝶呤 恶性淋巴瘤 化疗 护理 

分 类 号：R473[医药卫生—护理学]